SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ngm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 ALA A 256
ASP A 253
GLY A 224
GLY A 223
THR A 249
 None
 1.10A 2c49A-3ngmA:
undetectable		 2c49A-3ngmA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		3 / 3 GLY A  64
TYR A  65
SER A  26
 None
 0.77A 2xatA-3ngmA:
undetectable		 2xatA-3ngmA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 VAL A 200
HIS A 257
ASP A 198
GLY A  81
SER A 144
 None
 0.96A 3sufB-3ngmA:
undetectable		 3sufB-3ngmA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 TYR A  15
GLY A  10
ASN A  11
ILE A 231
LEU A 219
 None
 1.49A 4kovA-3ngmA:
undetectable		 4kovA-3ngmA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 LEU A 157
GLY A  63
GLY A  64
ALA A 153
GLY A  19
 None
 0.98A 4n09B-3ngmA:
undetectable		 4n09B-3ngmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 LEU A 157
GLY A  63
GLY A  64
ALA A 153
GLY A  19
 None
 0.99A 4n09D-3ngmA:
undetectable		 4n09D-3ngmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 ASP A 198
THR A 151
ALA A 150
ALA A 148
TYR A 260
 None
 1.21A 4u15A-3ngmA:
undetectable		 4u15A-3ngmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 ASP A 198
THR A 151
ALA A 150
ALA A 148
TYR A 260
 None
 1.16A 4u15B-3ngmA:
undetectable		 4u15B-3ngmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 12 GLU A 238
PHE A 261
ILE A  16
TYR A 169
GLY A  10
 None
 1.36A 5esgA-3ngmA:
undetectable		 5esgA-3ngmA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		3 / 3 ARG A 202
ASN A 301
ASP A 293
 None
 0.71A 5gwxA-3ngmA:
undetectable		 5gwxA-3ngmA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3ngm EXTRACELLULAR LIPASE
(Fusarium
graminearum) 		5 / 10 ALA A 122
ILE A 118
GLY A 146
PHE A  79
SER A  26
 None
 1.08A 5i6xA-3ngmA:
undetectable		 5i6xA-3ngmA:
18.94