SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 HIS A 665
SER A 661
ARG A 663
VAL A 657
 None
 1.35A 1u1jA-3nh9A:
undetectable		 1u1jA-3nh9A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 LEU A 769
ILE A 684
GLY A 687
VAL A 772
ILE A 737
 BME  A   3 ( 4.9A)
None
None
None
None
 1.13A 2r5qA-3nh9A:
undetectable		 2r5qA-3nh9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 LEU A 769
ILE A 684
GLY A 687
VAL A 772
ILE A 737
 BME  A   3 ( 4.9A)
None
None
None
None
 1.13A 2r5qC-3nh9A:
undetectable		 2r5qC-3nh9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 LEU A 583
SER A 661
THR A 658
VAL A 657
 None
 1.13A 2uz2A-3nh9A:
undetectable		 2uz2A-3nh9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 ARG A 634
ILE A 779
THR A 787
 ATP  A   1 (-3.3A)
None
BME  A   3 ( 4.3A)
 0.74A 3ia4D-3nh9A:
undetectable		 3ia4D-3nh9A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 TYR A 599
GLY A 800
PHE A 597
SER A 598
ASP A 799
 ATP  A   1 (-3.2A)
None
None
None
None
 1.31A 3nmuA-3nh9A:
undetectable
3nmuF-3nh9A:
undetectable		 3nmuA-3nh9A:
23.76
3nmuF-3nh9A:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 TYR A 716
ARG A 717
ALA A 681
ARG A 685
 None
 1.13A 3twpA-3nh9A:
undetectable		 3twpA-3nh9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 621
LEU A 749
ILE A 590
ILE A 632
PHE A 637
 None
None
None
None
BME  A   2 ( 4.4A)
 1.42A 4a79B-3nh9A:
undetectable		 4a79B-3nh9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLN A 617
VAL A 613
ILE A 590
PRO A 745
ILE A 666
 None
 1.13A 4drhD-3nh9A:
undetectable		 4drhD-3nh9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 ALA A 620
ALA A 782
LEU A 785
LEU A 795
VAL A 796
 None
 1.12A 4or0B-3nh9A:
undetectable		 4or0B-3nh9A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLY A 581
PRO A 582
GLN A 652
 None
 0.60A 4qwpB-3nh9A:
undetectable		 4qwpB-3nh9A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 6 LEU A 795
LEU A 606
ILE A 590
PHE A 592
 None
 1.16A 4y4dA-3nh9A:
undetectable		 4y4dA-3nh9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 6 ILE A 680
PHE A 712
ILE A 705
GLU A 731
 None
 0.92A 4zzcA-3nh9A:
undetectable
4zzcB-3nh9A:
undetectable		 4zzcA-3nh9A:
22.16
4zzcB-3nh9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		4 / 6 ILE A 680
PHE A 712
ILE A 705
GLU A 731
 None
 0.98A 4zzcB-3nh9A:
undetectable
4zzcC-3nh9A:
undetectable		 4zzcB-3nh9A:
22.16
4zzcC-3nh9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 583
ILE A 632
ARG A 648
ILE A 654
LEU A 749
 None
 1.08A 5h8tA-3nh9A:
undetectable		 5h8tA-3nh9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 GLY A 626
VAL A 781
ILE A 797
GLY A 800
LEU A 606
 ATP  A   1 (-3.5A)
None
None
None
None
 0.88A 5vkqC-3nh9A:
undetectable
5vkqD-3nh9A:
undetectable		 5vkqC-3nh9A:
10.69
5vkqD-3nh9A:
10.69