SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		3 / 3 MET A  26
LEU A  29
SER A  30
 None
 0.59A 1ee2A-3nhvA:
undetectable		 1ee2A-3nhvA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		5 / 10 ASP A  53
ILE A  65
ILE A 123
GLY A 121
ILE A 120
 None
 1.05A 1sh9B-3nhvA:
undetectable		 1sh9B-3nhvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		4 / 4 ARG A 115
ASP A  53
GLY A 122
THR A  33
 None
 1.29A 3k4vB-3nhvA:
undetectable		 3k4vB-3nhvA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A 127
ARG A  55
ASP A 142
 None
 0.95A 3wipG-3nhvA:
undetectable
3wipH-3nhvA:
undetectable		 3wipG-3nhvA:
20.70
3wipH-3nhvA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		5 / 12 ALA A 102
ALA A 110
PHE A 109
ILE A  50
ILE A  71
 None
 1.04A 4kjjA-3nhvA:
undetectable		 4kjjA-3nhvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3nhv BH2092 PROTEIN
(Bacillus
halodurans) 		6 / 12 ILE A  76
ALA A 110
PHE A 109
ILE A  50
LEU A  84
ILE A  71
 None
 1.31A 4kjjA-3nhvA:
undetectable		 4kjjA-3nhvA:
22.56