SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		6 / 10 ALA A  41
ALA A  44
LEU A  48
LEU A   9
ALA A  33
LEU A  55
 None
 1.28A 2bxgB-3nhzA:
undetectable		 2bxgB-3nhzA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  65
GLY A  64
ILE A  79
VAL A  11
GLY A  94
 None
 0.93A 3bwcA-3nhzA:
3.2		 3bwcA-3nhzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  65
GLY A  64
ILE A  79
VAL A  11
GLY A  94
 None
 0.98A 3bwcB-3nhzA:
3.0		 3bwcB-3nhzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 112
ARG A 115
THR A  32
ILE A   8
LEU A  21
 None
 1.03A 3k2hA-3nhzA:
2.1		 3k2hA-3nhzA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  27
GLY A  29
ARG A   5
ILE A  23
GLU A  19
 None
 1.14A 5bw4A-3nhzA:
undetectable		 5bw4A-3nhzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		4 / 5 LEU A 112
LEU A  17
THR A  83
PRO A  60
 None
 0.95A 6ew0F-3nhzA:
undetectable		 6ew0F-3nhzA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3nhz TWO COMPONENT SYSTEM
TRANSCRIPTIONAL
REGULATOR MTRA
(Mycobacterium
tuberculosis) 		4 / 6 LEU A 112
LEU A  17
THR A  83
PRO A  60
 None
 0.95A 6ew0G-3nhzA:
undetectable		 6ew0G-3nhzA:
22.83