SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ni7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWZ_B_BEZB301_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.04A	5ewzB-3ni7A: undetectable	5ewzB-3ni7A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M35_B_BEZB302_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.04A	5m35B-3ni7A: undetectable	5m35B-3ni7A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M36_A_BEZA303_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.05A	5m36A-3ni7A: 2.3	5m36A-3ni7A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_F_CCSF14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	4 / 6	PHE A 162 LEU A 178 SER A 171 ARG A 99	None	0.98A	5o4yF-3ni7A: undetectable	5o4yF-3ni7A: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FN9_A_BEZA302_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.04A	6fn9A-3ni7A: undetectable	6fn9A-3ni7A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNA_B_BEZB302_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.06A	6fnaB-3ni7A: 3.4	6fnaB-3ni7A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNB_A_BEZA301_0 (14-3-3 PROTEIN ZETA/DELTA)	3ni7	BACTERIAL REGULATORY PROTEINS, TETR FAMILY (Nitrosomonas europaea)	3 / 3	MET A 105 GLN A 104 ARG A 103	None	1.04A	6fnbA-3ni7A: 2.1	6fnbA-3ni7A: 22.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5EWZ_B_BEZB301_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.04A","5ewzB-3ni7A:undetectable","5ewzB-3ni7A:22.35"],["5M35_B_BEZB302_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.04A","5m35B-3ni7A:undetectable","5m35B-3ni7A:21.07"],["5M36_A_BEZA303_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.05A","5m36A-3ni7A:2.3","5m36A-3ni7A:21.07"],["5O4Y_F_CCSF14_0","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",4,"PHE A 162;LEU A 178;SER A 171;ARG A  99","None","0.98A","5o4yF-3ni7A:undetectable","5o4yF-3ni7A:12.00"],["6FN9_A_BEZA302_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.04A","6fn9A-3ni7A:undetectable","6fn9A-3ni7A:22.35"],["6FNA_B_BEZB302_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.06A","6fnaB-3ni7A:3.4","6fnaB-3ni7A:22.35"],["6FNB_A_BEZA301_0","14-3-3 PROTEIN ZETA\/DELTA","3ni7","BACTERIAL REGULATORY PROTEINS, TETR FAMILY","Nitrosomonas europaea",3,"MET A 105;GLN A 104;ARG A 103","None","1.04A","6fnbA-3ni7A:2.1","6fnbA-3ni7A:22.35"]]