SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 7 LEU A  86
LEU A 161
THR A 148
VAL A 144
 None
 1.01A 1dvxB-3nibA:
undetectable		 1dvxB-3nibA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 12 LEU A  86
VAL A  89
ALA A  70
LEU A  75
PHE A 155
 None
 1.09A 1gs4A-3nibA:
undetectable		 1gs4A-3nibA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 7 LEU A  68
THR A  66
LEU A  42
GLY A  46
LEU A  48
 None
None
GOL  A 277 ( 4.4A)
None
None
 1.49A 1gtiA-3nibA:
undetectable		 1gtiA-3nibA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 6 LEU A  42
VAL A 189
ILE A  26
ARG A 175
 GOL  A 277 ( 4.4A)
None
None
None
 1.07A 1opjB-3nibA:
undetectable		 1opjB-3nibA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 12 ILE A 194
ALA A 174
LEU A 168
PHE A 176
LEU A  22
 None
 1.14A 1rb2B-3nibA:
undetectable		 1rb2B-3nibA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S2A_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 12 TYR A 254
LEU A  96
SER A 113
GLN A 255
PHE A 245
 None
 1.31A 1s2aA-3nibA:
undetectable		 1s2aA-3nibA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 3nib TEG14
(uncultured
soil
bacterium) 		3 / 3 ARG A  90
TYR A 165
LYS A 169
 GOL  A 278 (-3.4A)
NHE  A 276 (-4.7A)
NHE  A 276 ( 4.7A)
 0.89A 1uujB-3nibA:
undetectable		 1uujB-3nibA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 8 LYS A  65
SER A   9
ARG A  90
GLU A  43
 None
None
GOL  A 278 (-3.4A)
None
 1.39A 1xr2B-3nibA:
undetectable		 1xr2B-3nibA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3nib TEG14
(uncultured
soil
bacterium) 		3 / 3 GLN A 270
HIS A 266
ARG A 145
 None
 0.93A 1zlqA-3nibA:
undetectable		 1zlqA-3nibA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3nib TEG14
(uncultured
soil
bacterium) 		3 / 3 ASP A 184
ASP A 159
ASN A   2
 None
 0.81A 2bm9D-3nibA:
undetectable		 2bm9D-3nibA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.16A 4e47A-3nibA:
undetectable		 4e47A-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.13A 4e47B-3nibA:
undetectable		 4e47B-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.13A 4e47C-3nibA:
undetectable		 4e47C-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 5 ALA A 274
HIS A 259
GLN A 255
TYR A 254
 None
 1.22A 4gboB-3nibA:
undetectable		 4gboB-3nibA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.20A 4jdsA-3nibA:
undetectable		 4jdsA-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.19A 4jdsB-3nibA:
undetectable		 4jdsB-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.15A 4jdsC-3nibA:
undetectable		 4jdsC-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 12 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.20A 4jlgA-3nibA:
undetectable		 4jlgA-3nibA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3nib TEG14
(uncultured
soil
bacterium) 		3 / 3 VAL A  85
ALA A  83
PHE A 182
 None
 0.90A 4w5nA-3nibA:
3.6		 4w5nA-3nibA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nib TEG14
(uncultured
soil
bacterium) 		5 / 11 ILE A  95
GLY A 125
GLU A 124
GLY A 136
HIS A  67
 None
 1.07A 5ayfA-3nibA:
undetectable		 5ayfA-3nibA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 6 VAL A 144
ASN A  91
PRO A  92
GLU A 166
 None
 1.21A 6h7uA-3nibA:
undetectable		 6h7uA-3nibA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nib TEG14
(uncultured
soil
bacterium) 		4 / 5 ARG A 164
MET A 163
THR A 162
LEU A 161
 None
 1.17A 6nknW-3nibA:
undetectable		 6nknW-3nibA:
12.21