SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 3nic ECO29KIR
(Escherichia
coli) 		5 / 11 ILE A 105
LEU A 101
ILE A 129
THR A  32
PRO A  39
 None
 1.23A 3a50B-3nicA:
undetectable		 3a50B-3nicA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3nic ECO29KIR
(Escherichia
coli) 		5 / 11 ILE A 105
LEU A 101
ILE A 129
THR A  32
PRO A  39
 None
 1.17A 3a51A-3nicA:
undetectable		 3a51A-3nicA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3nic ECO29KIR
(Escherichia
coli) 		5 / 12 ILE A 105
LEU A 101
ILE A 129
THR A  32
PRO A  39
 None
 1.19A 3a51D-3nicA:
undetectable		 3a51D-3nicA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 3nic ECO29KIR
(Escherichia
coli) 		3 / 3 CYH A 125
HIS A  35
PHE A 127
 None
 1.03A 3cr4X-3nicA:
undetectable		 3cr4X-3nicA:
17.49