SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 8 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.39A 1v54C-3nj2A:
undetectable
1v54J-3nj2A:
undetectable		 1v54C-3nj2A:
20.45
1v54J-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 8 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.41A 2dyrC-3nj2A:
undetectable
2dyrJ-3nj2A:
undetectable		 2dyrC-3nj2A:
20.45
2dyrJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.41A 2eikC-3nj2A:
undetectable
2eikJ-3nj2A:
undetectable		 2eikC-3nj2A:
20.45
2eikJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 8 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.40A 3ag4C-3nj2A:
undetectable
3ag4J-3nj2A:
undetectable		 3ag4C-3nj2A:
20.45
3ag4J-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.38A 3asnC-3nj2A:
undetectable
3asnJ-3nj2A:
undetectable		 3asnC-3nj2A:
20.45
3asnJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		4 / 4 LEU A  87
ILE A  62
TYR A  92
TYR A  53
 None
 1.50A 3vt7A-3nj2A:
undetectable		 3vt7A-3nj2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.30A 3x2qC-3nj2A:
undetectable
3x2qJ-3nj2A:
undetectable		 3x2qC-3nj2A:
20.45
3x2qJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		4 / 4 LEU A 147
LEU A  60
GLN A  33
GLU A  25
 None
 1.04A 4i41A-3nj2A:
undetectable		 4i41A-3nj2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		3 / 3 VAL A 112
PHE A 142
ARG A  88
 None
 0.88A 4xr4B-3nj2A:
undetectable		 4xr4B-3nj2A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.31A 5b1aC-3nj2A:
undetectable
5b1aJ-3nj2A:
undetectable		 5b1aC-3nj2A:
20.45
5b1aJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.31A 5b1aP-3nj2A:
undetectable
5b1aW-3nj2A:
undetectable		 5b1aP-3nj2A:
20.45
5b1aW-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.35A 5b3sC-3nj2A:
undetectable
5b3sJ-3nj2A:
undetectable		 5b3sC-3nj2A:
20.45
5b3sJ-3nj2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.33A 5iy5C-3nj2A:
undetectable
5iy5J-3nj2A:
undetectable		 5iy5C-3nj2A:
20.38
5iy5J-3nj2A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nj2 DUF269-CONTAINING
PROTEIN
(Cyanothece
sp.
ATCC
51142) 		5 / 7 LEU A  40
GLN A  43
PHE A  36
LEU A 150
PHE A 144
 None
 1.35A 5z84C-3nj2A:
undetectable
5z84J-3nj2A:
undetectable		 5z84C-3nj2A:
20.45
5z84J-3nj2A:
16.86