SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3njp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 8 SER A 326
ASN A 328
ILE A 332
GLY A 315
 None
NAG  A1328 (-1.7A)
None
None
 0.86A 1meiA-3njpA:
undetectable		 1meiA-3njpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 6 GLN A  81
ASN A 115
ASN A  86
LEU A 120
 None
 1.07A 2nyrA-3njpA:
undetectable		 2nyrA-3njpA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A  77
ILE A  58
LEU A  80
VAL A  97
PHE A  31
 None
 1.31A 2qo6A-3njpA:
undetectable		 2qo6A-3njpA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 8 ILE A 143
LEU A  80
LEU A  77
PHE A 126
 None
 0.83A 2vctA-3njpA:
undetectable		 2vctA-3njpA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 8 ILE A 143
LEU A  80
LEU A  77
PHE A 126
 None
 0.80A 2vctB-3njpA:
undetectable		 2vctB-3njpA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 10 TYR A 447
ILE A 466
ASN A 449
VAL A 437
LEU A 424
 None
 1.29A 3ay0A-3njpA:
undetectable		 3ay0A-3njpA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 10 TYR A 447
ILE A 466
ASN A 449
VAL A 437
LEU A 424
 None
 1.29A 3ay0B-3njpA:
undetectable		 3ay0B-3njpA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 5 VAL A  37
VAL A  36
GLN A  81
PHE A  54
 None
 1.34A 3bjwH-3njpA:
undetectable		 3bjwH-3njpA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 5 VAL A  37
VAL A  36
GLN A  81
PHE A  54
 None
 1.34A 3bjwB-3njpA:
undetectable		 3bjwB-3njpA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 8 GLY A 315
GLY A 343
GLY A 379
ILE A 402
 None
 0.61A 3d41A-3njpA:
undetectable		 3d41A-3njpA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 11 GLN A 184
LEU A  80
VAL A  65
PHE A 126
PHE A 156
 None
 1.40A 3n23C-3njpA:
undetectable		 3n23C-3njpA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 368
VAL A 374
GLY A 315
ILE A 316
LEU A 371
 None
 0.90A 3ogqA-3njpA:
undetectable		 3ogqA-3njpA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 7 ASN A  86
ALA A  62
ARG A 231
ALA A 265
 None
 0.96A 3twpA-3njpA:
undetectable		 3twpA-3njpA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 7 ASN A  86
ALA A  62
ARG A 231
ALA A 265
 None
 1.11A 3twpC-3njpA:
undetectable		 3twpC-3njpA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 497
ASP A 369
GLN A 366
 None
 0.91A 4azsA-3njpA:
undetectable		 4azsA-3njpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 5 SER A 423
GLY A 425
THR A 450
VAL A 500
 None
 1.05A 4eohA-3njpA:
undetectable		 4eohA-3njpA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 7 ILE A 432
LEU A 426
LEU A 381
ILE A 377
 None
 0.86A 4rmjA-3njpA:
undetectable		 4rmjA-3njpA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		3 / 3 PRO A 112
ARG A 114
GLU A 110
 None
 0.92A 5j6hA-3njpA:
undetectable		 5j6hA-3njpA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 6 ARG A 403
GLY A 379
GLU A 376
SER A 340
 None
 1.14A 5ny7A-3njpA:
undetectable		 5ny7A-3njpA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		3 / 3 LEU A 382
ASN A 442
LEU A 393
 None
 0.75A 6exiD-3njpA:
undetectable		 6exiD-3njpA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3njp EPIDERMAL GROWTH
FACTOR RECEPTOR
(Homo
sapiens) 		4 / 6 MET A 154
ALA A  94
LEU A  95
ALA A  96
 None
 1.16A 6fosB-3njpA:
undetectable		 6fosB-3njpA:
7.23