SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3njx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 6 THR A  33
SER A  29
SER A  28
VAL A  60
 None
 1.31A 2hdnI-3njxA:
undetectable
2hdnJ-3njxA:
undetectable
2hdnL-3njxA:
undetectable		 2hdnI-3njxA:
5.93
2hdnJ-3njxA:
21.74
2hdnL-3njxA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 6 SER A  28
VAL A  60
THR A  33
SER A  29
 None
 1.25A 2hdnJ-3njxA:
undetectable
2hdnK-3njxA:
undetectable
2hdnL-3njxA:
undetectable		 2hdnJ-3njxA:
21.74
2hdnK-3njxA:
5.93
2hdnL-3njxA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.95A 2ieoA-3njxA:
undetectable		 2ieoA-3njxA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.95A 2pymA-3njxA:
undetectable		 2pymA-3njxA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 9 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 1.05A 3ektA-3njxA:
undetectable		 3ektA-3njxA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		6 / 11 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
THR A 338
 None
CA  A 800 (-2.9A)
None
None
None
None
 1.37A 3ekxA-3njxA:
undetectable		 3ekxA-3njxA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 10 ILE A  51
SER A  57
GLY A  54
SER A  26
LEU A  78
 None
 1.38A 3ik6B-3njxA:
undetectable
3ik6E-3njxA:
undetectable		 3ik6B-3njxA:
16.93
3ik6E-3njxA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 10 SER A  26
LEU A  78
ILE A  51
SER A  57
GLY A  54
 None
 1.43A 3iluB-3njxA:
undetectable
3iluE-3njxA:
undetectable		 3iluB-3njxA:
16.93
3iluE-3njxA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 ILE A  51
SER A  57
GLY A  54
SER A  26
LEU A  78
 None
 1.40A 3iluB-3njxA:
undetectable
3iluE-3njxA:
undetectable		 3iluB-3njxA:
16.93
3iluE-3njxA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 8 GLU A 100
HIS A 221
ASN A 207
MET A 206
 None
 1.33A 3kp6A-3njxA:
undetectable
3kp6B-3njxA:
undetectable		 3kp6A-3njxA:
13.36
3kp6B-3njxA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 ASP A 368
ASN A 360
SER A 145
 None
 0.97A 3lslA-3njxA:
undetectable
3lslD-3njxA:
undetectable		 3lslA-3njxA:
17.52
3lslD-3njxA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 SER A 145
ASP A 368
ASN A 360
 None
 0.97A 3lslA-3njxA:
undetectable
3lslD-3njxA:
undetectable		 3lslA-3njxA:
17.52
3lslD-3njxA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.97A 3lzsA-3njxA:
undetectable		 3lzsA-3njxA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.96A 3lzsB-3njxA:
undetectable		 3lzsB-3njxA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 THR A 128
THR A 129
ALA A 130
SER A 149
SER A 114
 None
 1.12A 3mg02-3njxA:
undetectable
3mg0V-3njxA:
undetectable		 3mg02-3njxA:
20.28
3mg0V-3njxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 ASP A 190
GLY A 209
TYR A 205
 None
 0.78A 3w9tC-3njxA:
undetectable		 3w9tC-3njxA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 ASP A 190
GLY A 209
TYR A 205
 None
 0.78A 3w9tG-3njxA:
undetectable		 3w9tG-3njxA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 6 ILE A 238
ILE A  51
MET A  93
TRP A 204
 None
 1.36A 3weoA-3njxA:
undetectable		 3weoA-3njxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 8 SER A 424
ASN A 498
THR A 421
GLY A 460
 None
 0.89A 4fo4A-3njxA:
undetectable		 4fo4A-3njxA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 6 ARG A 418
GLY A 420
GLN A 310
MET A 271
 None
 1.27A 4g0vB-3njxA:
undetectable		 4g0vB-3njxA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 TYR A 287
GLN A 351
TRP A 273
 None
 0.90A 4kn2C-3njxA:
undetectable		 4kn2C-3njxA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 7 PHE A 151
ASP A 190
SER A 208
SER A 450
 None
 1.07A 4lv9A-3njxA:
undetectable
4lv9B-3njxA:
undetectable		 4lv9A-3njxA:
21.81
4lv9B-3njxA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 1.01A 4njvB-3njxA:
undetectable		 4njvB-3njxA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.93A 4njvC-3njxA:
undetectable		 4njvC-3njxA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 ALA A 210
SER A 208
GLU A 312
GLY A 460
TYR A 458
 None
 1.16A 4r29B-3njxA:
undetectable		 4r29B-3njxA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 ILE A  13
HIS A  85
VAL A  84
HIS A  92
ILE A  91
 None
 1.11A 4rvdA-3njxA:
undetectable		 4rvdA-3njxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 SER A 241
ALA A 253
VAL A 252
 None
 0.60A 4x1iA-3njxA:
undetectable		 4x1iA-3njxA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 ASN A 207
GLU A 214
GLY A 185
TYR A 216
TYR A 179
 None
 1.50A 5fhrB-3njxA:
undetectable		 5fhrB-3njxA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		4 / 5 HIS A 188
ALA A 210
SER A 208
TYR A 216
 None
 1.31A 5yodF-3njxA:
0.5		 5yodF-3njxA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.95A 6dj1B-3njxA:
undetectable		 6dj1B-3njxA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 12 GLY A 346
ASP A 349
VAL A 336
GLY A 420
ILE A 419
 None
CA  A 800 (-2.9A)
None
None
None
 0.97A 6dj2B-3njxA:
undetectable		 6dj2B-3njxA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 10 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.00A 6ebpD-3njxA:
undetectable		 6ebpD-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.03A 6ebzA-3njxA:
undetectable		 6ebzA-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.03A 6ebzB-3njxA:
undetectable		 6ebzB-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.04A 6ebzC-3njxA:
undetectable		 6ebzC-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.00A 6ebzD-3njxA:
undetectable		 6ebzD-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		3 / 3 ARG A 107
PHE A 108
GLY A  52
 SO4  A 904 (-3.7A)
None
None
 0.72A 6fgdA-3njxA:
undetectable		 6fgdA-3njxA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3njx RHAMNOGALACTURONASE
B
(Aspergillus
aculeatus) 		5 / 11 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
 None
 1.07A 6gp2A-3njxA:
undetectable		 6gp2A-3njxA:
9.49