SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nkg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_B_EAAB213_1 (GLUTATHIONE S-TRANSFERASE P)	3nkg	UNCHARACTERIZED PROTEIN GEBA250068378 (Sulfurospirillum deleyianum)	4 / 7	TYR A 88 VAL A 94 ASN A 123 GLY A 122	None None ACY A 175 (-3.1A) None	1.14A	3kmoB-3nkgA: undetectable	3kmoB-3nkgA: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_A_NCTA501_1 (CYTOCHROME P450 2A6)	3nkg	UNCHARACTERIZED PROTEIN GEBA250068378 (Sulfurospirillum deleyianum)	5 / 7	PHE A 35 ASN A 123 GLY A 122 THR A 120 ILE A 132	None ACY A 175 (-3.1A) None None None	1.45A	4ejjA-3nkgA: undetectable	4ejjA-3nkgA: 16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_E_FK5E201_1 (FK506-BINDING PROTEIN 1)	3nkg	UNCHARACTERIZED PROTEIN GEBA250068378 (Sulfurospirillum deleyianum)	5 / 11	ASP A 161 PHE A 35 ILE A 132 ILE A 146 ILE A 6	None	1.10A	5hw8E-3nkgA: undetectable	5hw8E-3nkgA: 24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_F_FK5F201_1 (FK506-BINDING PROTEIN 1)	3nkg	UNCHARACTERIZED PROTEIN GEBA250068378 (Sulfurospirillum deleyianum)	5 / 12	ASP A 161 PHE A 35 ILE A 132 ILE A 146 ILE A 6	None	1.13A	5hw8B-3nkgA: undetectable 5hw8F-3nkgA: undetectable 5hw8G-3nkgA: undetectable	5hw8B-3nkgA: 24.04 5hw8F-3nkgA: 24.04 5hw8G-3nkgA: 24.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KMO_B_EAAB213_1","GLUTATHIONE S-TRANSFERASE P","3nkg","UNCHARACTERIZED PROTEIN GEBA250068378","Sulfurospirillum deleyianum",4,"TYR A  88;VAL A  94;ASN A 123;GLY A 122","None;None;ACY A 175 (-3.1A);None","1.14A","3kmoB-3nkgA:undetectable","3kmoB-3nkgA:20.19"],["4EJJ_A_NCTA501_1","CYTOCHROME P450 2A6","3nkg","UNCHARACTERIZED PROTEIN GEBA250068378","Sulfurospirillum deleyianum",5,"PHE A  35;ASN A 123;GLY A 122;THR A 120;ILE A 132","None;ACY A 175 (-3.1A);None;None;None","1.45A","4ejjA-3nkgA:undetectable","4ejjA-3nkgA:16.28"],["5HW8_E_FK5E201_1","FK506-BINDING PROTEIN 1","3nkg","UNCHARACTERIZED PROTEIN GEBA250068378","Sulfurospirillum deleyianum",5,"ASP A 161;PHE A  35;ILE A 132;ILE A 146;ILE A   6","None","1.10A","5hw8E-3nkgA:undetectable","5hw8E-3nkgA:24.04"],["5HW8_F_FK5F201_1","FK506-BINDING PROTEIN 1;FK506-BINDING PROTEIN 1;FK506-BINDING PROTEIN 1","3nkg","UNCHARACTERIZED PROTEIN GEBA250068378","Sulfurospirillum deleyianum",5,"ASP A 161;PHE A  35;ILE A 132;ILE A 146;ILE A   6","None","1.13A","5hw8B-3nkgA:undetectable;5hw8F-3nkgA:undetectable;5hw8G-3nkgA:undetectable","5hw8B-3nkgA:24.04;5hw8F-3nkgA:24.04;5hw8G-3nkgA:24.04"]]