SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nkh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		5 / 12 PHE A  39
LYS A 108
ILE A  53
PHE A 130
GLY A  97
 None
 1.24A 2lbdA-3nkhA:
undetectable		 2lbdA-3nkhA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		5 / 10 ILE A  11
ILE A   7
ASN A  15
VAL A 160
ILE A 146
 None
 1.24A 2nnhB-3nkhA:
undetectable		 2nnhB-3nkhA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		4 / 7 MET A  45
LEU A 165
PHE A 130
VAL A 129
 None
 1.15A 3jwqC-3nkhA:
undetectable		 3jwqC-3nkhA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		3 / 3 LEU A  65
ILE A  96
ARG A  94
 None
 0.63A 4mk4B-3nkhA:
undetectable		 4mk4B-3nkhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		4 / 8 SER A 197
SER A  -2
HIS A 201
GLU A 204
 None
 1.06A 4ms4A-3nkhA:
undetectable		 4ms4A-3nkhA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3nkh INTEGRASE
(Staphylococcus
aureus) 		3 / 3 ASP A  57
VAL A 129
LEU A 106
 None
 0.36A 5e5jB-3nkhA:
undetectable		 5e5jB-3nkhA:
18.41