SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3nkl UDP-D-QUINOVOSAMINE
4-DEHYDROGENASE
(Aliivibrio
fischeri) 		4 / 6 ILE A  29
VAL A  66
LEU A  68
ILE A   6
 None
 0.84A 4asdA-3nklA:
undetectable		 4asdA-3nklA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3nkl UDP-D-QUINOVOSAMINE
4-DEHYDROGENASE
(Aliivibrio
fischeri) 		5 / 12 GLY A  45
ILE A  46
ILE A 108
ALA A  69
LEU A 111
 None
 1.05A 5e72A-3nklA:
undetectable		 5e72A-3nklA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 3nkl UDP-D-QUINOVOSAMINE
4-DEHYDROGENASE
(Aliivibrio
fischeri) 		5 / 11 ARG A  36
VAL A  80
ILE A  81
TYR A   7
ILE A  32
 SO4  A 145 ( 4.9A)
None
None
None
None
 1.02A 5hw8E-3nklA:
undetectable		 5hw8E-3nklA:
26.80