SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 VAL A 342
VAL A 352
TRP A 143
 None
 0.66A 1av2C-3nlcA:
undetectable
1av2D-3nlcA:
undetectable		 1av2C-3nlcA:
2.41
1av2D-3nlcA:
2.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 ALA A 504
GLY A 104
GLY A 264
GLY A 507
PHE A 229
ARG A 228
 None
FAD  A 601 (-3.1A)
FAD  A 601 (-3.2A)
None
None
None
 1.27A 1ej0A-3nlcA:
undetectable		 1ej0A-3nlcA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 8 MET A 281
ARG A 268
VAL A 263
GLY A 264
 None
None
FAD  A 601 (-3.7A)
FAD  A 601 (-3.2A)
 0.91A 1hrkA-3nlcA:
undetectable		 1hrkA-3nlcA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 8 MET A 281
ARG A 268
VAL A 263
GLY A 264
 None
None
FAD  A 601 (-3.7A)
FAD  A 601 (-3.2A)
 0.83A 1hrkB-3nlcA:
2.8		 1hrkB-3nlcA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 5 SER A 368
PHE A 467
VAL A 371
PHE A 333
 None
 1.20A 1oipA-3nlcA:
undetectable		 1oipA-3nlcA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ILE A 101
LEU A 116
GLY A 113
VAL A 528
ALA A 527
 None
 1.15A 1tlsA-3nlcA:
undetectable		 1tlsA-3nlcA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ILE A 101
LEU A 116
GLY A 113
VAL A 528
ALA A 527
 None
 1.12A 1tlsB-3nlcA:
undetectable		 1tlsB-3nlcA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 VAL A 342
VAL A 352
TRP A 143
 None
 0.63A 1w5uC-3nlcA:
undetectable
1w5uD-3nlcA:
undetectable		 1w5uC-3nlcA:
2.41
1w5uD-3nlcA:
2.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 5 ALA A 408
TYR A 406
ALA A 398
TYR A 399
 None
 0.93A 1xl6A-3nlcA:
undetectable
1xl6B-3nlcA:
undetectable		 1xl6A-3nlcA:
22.45
1xl6B-3nlcA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 SER A 431
GLY A 476
VAL A 352
ALA A 398
ALA A 408
 None
 1.34A 2avdB-3nlcA:
undetectable		 2avdB-3nlcA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ARG A 489
PHE A 105
ALA A 504
ILE A 125
ILE A 220
 None
 1.26A 2bjfA-3nlcA:
undetectable		 2bjfA-3nlcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 SER A 495
THR A 244
GLN A 242
 None
 0.83A 2fk8A-3nlcA:
2.2		 2fk8A-3nlcA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 VAL A 352
TRP A 143
VAL A 342
 None
 0.76A 2izqA-3nlcA:
undetectable
2izqB-3nlcA:
undetectable		 2izqA-3nlcA:
2.41
2izqB-3nlcA:
2.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 7 MET A 281
ILE A 388
ARG A 268
PRO A 503
 None
 1.19A 2pnjB-3nlcA:
undetectable		 2pnjB-3nlcA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 160
GLY A 157
GLU A 127
ARG A 128
THR A 139
 FAD  A 601 (-3.4A)
FAD  A 601 (-4.1A)
FAD  A 601 (-2.6A)
FAD  A 601 (-4.4A)
None
 1.17A 2vdvE-3nlcA:
2.5		 2vdvE-3nlcA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 11 GLY A 160
GLY A 157
GLU A 127
ARG A 128
THR A 139
 FAD  A 601 (-3.4A)
FAD  A 601 (-4.1A)
FAD  A 601 (-2.6A)
FAD  A 601 (-4.4A)
None
 1.16A 2vdvF-3nlcA:
2.8		 2vdvF-3nlcA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.29A 2wa2B-3nlcA:
undetectable		 2wa2B-3nlcA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 4 ALA A 408
TYR A 406
ALA A 398
TYR A 399
 None
 0.88A 2wlkA-3nlcA:
undetectable
2wlkB-3nlcA:
undetectable		 2wlkA-3nlcA:
22.45
2wlkB-3nlcA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 7 GLY A 106
ALA A 517
VAL A 260
ILE A 125
 FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
None
None
 0.75A 3a2qA-3nlcA:
undetectable		 3a2qA-3nlcA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 11 VAL A 115
LEU A 116
GLY A 113
ILE A 125
PRO A 107
 None
None
None
None
FAD  A 601 (-3.8A)
 1.33A 3bjwE-3nlcA:
undetectable		 3bjwE-3nlcA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 504
GLY A 106
GLY A 264
GLY A 507
ILE A 213
 None
FAD  A 601 (-3.3A)
FAD  A 601 (-3.2A)
None
None
 0.90A 3douA-3nlcA:
undetectable		 3douA-3nlcA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ILE A 103
ILE A 124
GLU A 226
ILE A 227
VAL A 246
 FAD  A 601 (-4.6A)
None
None
None
None
 1.23A 3fpjB-3nlcA:
3.4		 3fpjB-3nlcA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 PRO A 409
PHE A 290
ALA A 444
 None
 0.64A 3itaD-3nlcA:
undetectable		 3itaD-3nlcA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 8 THR A 479
GLN A 155
SER A 346
ARG A 268
 None
FAD  A 601 ( 4.1A)
None
None
 1.16A 3kp2A-3nlcA:
undetectable
3kp2B-3nlcA:
undetectable		 3kp2A-3nlcA:
15.12
3kp2B-3nlcA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 VAL A 342
VAL A 352
TRP A 143
 None
 0.84A 3l8lA-3nlcA:
undetectable
3l8lB-3nlcA:
undetectable		 3l8lA-3nlcA:
2.41
3l8lB-3nlcA:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 VAL A 342
VAL A 352
TRP A 143
 None
 0.58A 3l8lC-3nlcA:
undetectable
3l8lD-3nlcA:
undetectable		 3l8lC-3nlcA:
2.41
3l8lD-3nlcA:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 10 LEU A 261
TYR A 280
GLY A 509
VAL A 485
GLY A 507
 None
 0.96A 3ls4H-3nlcA:
undetectable		 3ls4H-3nlcA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 5 LEU A 248
THR A 231
GLU A 252
HIS A 237
 None
 1.35A 3n58C-3nlcA:
undetectable		 3n58C-3nlcA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 289
ALA A 369
THR A 353
ILE A 453
ALA A 449
VAL A 288
 None
 1.30A 3nvkI-3nlcA:
undetectable		 3nvkI-3nlcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.88A 3p97A-3nlcA:
2.2		 3p97A-3nlcA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.23A 3p97C-3nlcA:
undetectable		 3p97C-3nlcA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.88A 3p97C-3nlcA:
undetectable		 3p97C-3nlcA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 9 ALA A 366
GLY A 472
ILE A 413
ILE A 464
ILE A 299
 None
 0.89A 3s43A-3nlcA:
undetectable		 3s43A-3nlcA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 9 ALA A 366
GLY A 472
ILE A 413
ILE A 464
ILE A 299
 None
 0.92A 3s45A-3nlcA:
undetectable		 3s45A-3nlcA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 PHE A 467
SER A 368
SER A 332
 None
 0.82A 3ufgB-3nlcA:
undetectable		 3ufgB-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.24A 4ctjA-3nlcA:
undetectable		 4ctjA-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.24A 4ctjC-3nlcA:
undetectable		 4ctjC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.86A 4ctjC-3nlcA:
undetectable		 4ctjC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.85A 4ctkA-3nlcA:
undetectable		 4ctkA-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.23A 4ctkC-3nlcA:
2.1		 4ctkC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.85A 4ctkC-3nlcA:
2.1		 4ctkC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 11 ILE A 487
ALA A 508
GLY A 509
GLU A 506
GLY A 521
 None
None
None
FAD  A 601 (-2.9A)
None
 1.20A 4e47C-3nlcA:
undetectable		 4e47C-3nlcA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 PHE A  72
GLU A   6
LEU A  57
ILE A  59
LEU A  68
 None
 1.35A 4k38B-3nlcA:
undetectable		 4k38B-3nlcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 PHE A  72
GLU A   6
LEU A  57
ILE A  59
LEU A  68
 None
 1.27A 4k39A-3nlcA:
undetectable		 4k39A-3nlcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 9 ILE A 243
GLY A 245
ILE A 254
ILE A 532
VAL A 528
 None
 0.97A 4nptA-3nlcA:
undetectable		 4nptA-3nlcA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 ASP A 379
VAL A 288
LEU A 394
 None
 0.49A 5e5jB-3nlcA:
undetectable		 5e5jB-3nlcA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.88A 5e9qA-3nlcA:
undetectable		 5e9qA-3nlcA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.86A 5e9qC-3nlcA:
2.4		 5e9qC-3nlcA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.88A 5ec8A-3nlcA:
undetectable		 5ec8A-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.29A 5ec8C-3nlcA:
undetectable		 5ec8C-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.89A 5ec8C-3nlcA:
undetectable		 5ec8C-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.85A 5ehgA-3nlcA:
undetectable		 5ehgA-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
FAD  A 601 (-3.9A)
 0.97A 5ehgC-3nlcA:
undetectable		 5ehgC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.87A 5eifA-3nlcA:
undetectable		 5eifA-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.86A 5eifC-3nlcA:
undetectable		 5eifC-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.23A 5ekxB-3nlcA:
undetectable		 5ekxB-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.88A 5ekxB-3nlcA:
undetectable		 5ekxB-3nlcA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		3 / 3 SER A 249
LEU A 274
MET A 273
 None
 0.86A 5ikrB-3nlcA:
undetectable		 5ikrB-3nlcA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 511
ILE A 299
TYR A 318
GLY A 338
PHE A 333
 None
 0.96A 5jlcA-3nlcA:
undetectable		 5jlcA-3nlcA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
FAD  A 601 (-3.9A)
 0.97A 5kqrA-3nlcA:
undetectable		 5kqrA-3nlcA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.83A 5kqrA-3nlcA:
undetectable		 5kqrA-3nlcA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.85A 5kqsA-3nlcA:
undetectable		 5kqsA-3nlcA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 6 GLU A 347
ARG A 350
ARG A 480
ARG A 392
 None
 1.04A 5l6eA-3nlcA:
undetectable
5l6eB-3nlcA:
undetectable		 5l6eA-3nlcA:
19.47
5l6eB-3nlcA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.85A 5m5bA-3nlcA:
undetectable		 5m5bA-3nlcA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.83A 5njvA-3nlcA:
undetectable		 5njvA-3nlcA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.81A 5njvB-3nlcA:
undetectable		 5njvB-3nlcA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		6 / 12 GLY A 104
GLY A 162
GLY A 159
THR A 163
GLU A 158
ILE A 514
 FAD  A 601 (-3.1A)
FAD  A 601 (-3.1A)
None
None
None
FAD  A 601 (-3.9A)
 1.18A 5njvD-3nlcA:
undetectable		 5njvD-3nlcA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.78A 5njvD-3nlcA:
undetectable		 5njvD-3nlcA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		4 / 8 GLU A 470
GLY A 472
GLN A 411
LEU A 474
 None
 0.96A 5sxqA-3nlcA:
undetectable		 5sxqA-3nlcA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 410
PRO A 409
GLY A 402
ASP A 471
GLY A 426
 None
 1.24A 5wwsB-3nlcA:
undetectable		 5wwsB-3nlcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.76A 5wz1B-3nlcA:
undetectable		 5wz1B-3nlcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.83A 5wz2A-3nlcA:
undetectable		 5wz2A-3nlcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.81A 5wz2B-3nlcA:
undetectable		 5wz2B-3nlcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 264
GLY A 162
GLY A 160
THR A 163
ILE A 514
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.1A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.9A)
 0.79A 5wz2C-3nlcA:
undetectable		 5wz2C-3nlcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3nlc UNCHARACTERIZED
PROTEIN VP0956
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 435
PRO A 409
ALA A 410
ASP A 407
THR A 433
 None
 1.14A 5x6yC-3nlcA:
undetectable		 5x6yC-3nlcA:
21.39