SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
5 / 11 LEU A 138
ILE A 135
PRO A 161
TYR A 228
HIS A 218
None
1.41A 1s9aA-3nmbA:
undetectable
1s9aA-3nmbA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 7 TYR A 137
HIS A 218
LEU A 226
MET A 238
None
1.19A 1tuvA-3nmbA:
undetectable
1tuvA-3nmbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 7 SER A 186
ALA A 193
SER A 184
ASN A 168
None
0.73A 2i91A-3nmbA:
undetectable
2i91A-3nmbA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 7 SER A 186
ALA A 193
SER A 184
ASN A 168
None
0.74A 2i91B-3nmbA:
undetectable
2i91B-3nmbA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 6 GLU A 223
ALA A 185
PRO A 195
ALA A 193
None
1.16A 2zgwB-3nmbA:
undetectable
2zgwB-3nmbA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
5 / 10 VAL A 286
PHE A 119
VAL A  56
VAL A  36
LEU A  38
EDO  A   9 (-4.4A)
None
None
None
None
0.90A 3gwxA-3nmbA:
undetectable
3gwxA-3nmbA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 6 LEU A 123
PHE A 279
ILE A 135
PHE A 267
None
1.00A 3ko0S-3nmbA:
undetectable
3ko0S-3nmbA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 7 LEU A 230
LEU A 138
CYH A 259
ASN A 258
None
1.05A 3lm8B-3nmbA:
undetectable
3lm8D-3nmbA:
undetectable
3lm8B-3nmbA:
24.46
3lm8D-3nmbA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
4 / 8 LEU A 230
LEU A 138
CYH A 259
ASN A 258
None
1.01A 3lm8B-3nmbA:
undetectable
3lm8D-3nmbA:
undetectable
3lm8B-3nmbA:
24.46
3lm8D-3nmbA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
5 / 12 ALA A 241
PHE A 119
ILE A 268
GLY A 266
THR A 236
None
1.33A 5jlcA-3nmbA:
undetectable
5jlcA-3nmbA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
5 / 12 SER A  41
GLY A  75
GLY A  77
ASP A 106
THR A  83
None
0.96A 5kpcB-3nmbA:
undetectable
5kpcB-3nmbA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)
3nmb PUTATIVE SUGAR
HYDROLASE

(Bacteroides
ovatus)
5 / 12 GLY A  72
VAL A  81
SER A  51
LEU A  52
LEU A  54
None
None
None
None
EDO  A   7 ( 4.7A)
0.97A 5ubbA-3nmbA:
undetectable
5ubbA-3nmbA:
20.21