SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3nmr CUGBP ELAV-LIKE
FAMILY MEMBER 1
(Homo
sapiens) 		4 / 8 GLY A 113
MET A 168
PHE A 128
ILE A 124
 G  B   3 ( 3.2A)
None
None
None
 0.85A 4j4vC-3nmrA:
undetectable		 4j4vC-3nmrA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3nmr CUGBP ELAV-LIKE
FAMILY MEMBER 1
(Homo
sapiens) 		5 / 9 ALA A 164
THR A 163
ALA A 167
ILE A 134
GLY A 132
 None
 1.13A 4qvqK-3nmrA:
undetectable
4qvqL-3nmrA:
undetectable		 4qvqK-3nmrA:
20.74
4qvqL-3nmrA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3nmr CUGBP ELAV-LIKE
FAMILY MEMBER 1
(Homo
sapiens) 		5 / 9 ALA A 164
THR A 163
ALA A 167
ILE A 134
GLY A 132
 None
 1.13A 4qvqY-3nmrA:
undetectable
4qvqZ-3nmrA:
undetectable		 4qvqY-3nmrA:
20.74
4qvqZ-3nmrA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3nmr CUGBP ELAV-LIKE
FAMILY MEMBER 1
(Homo
sapiens) 		4 / 7 TRP A  27
THR A  26
PRO A  24
SER A  58
 None
 1.02A 5b6iA-3nmrA:
undetectable		 5b6iA-3nmrA:
16.87