SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		4 / 7 HIS A 177
LEU A 175
TYR A 110
ILE A 139
 None
CYN  A 245 ( 4.0A)
PO4  A 240 ( 4.4A)
HEM  A 239 (-3.8A)
 1.11A 1tuvA-3nn2A:
5.1		 1tuvA-3nn2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		4 / 7 TYR A 176
HIS A  72
LEU A  52
MET A 226
 None
 1.20A 1tuvA-3nn2A:
5.1		 1tuvA-3nn2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		3 / 3 ASP A  66
PHE A 236
ARG A  59
 None
 0.78A 2a3aA-3nn2A:
undetectable		 2a3aA-3nn2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		4 / 7 GLU A 210
PHE A 190
ILE A 137
PHE A 198
 HEM  A 239 ( 4.8A)
HEM  A 239 (-4.0A)
HEM  A 239 ( 3.8A)
None
 1.01A 2qmzA-3nn2A:
undetectable
2qmzB-3nn2A:
undetectable		 2qmzA-3nn2A:
22.61
2qmzB-3nn2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		5 / 12 ASP A 230
PHE A  69
ARG A  90
GLY A  42
LEU A  43
 GOL  A 248 (-3.7A)
None
None
None
None
 1.11A 3j6pB-3nn2A:
undetectable		 3j6pB-3nn2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		5 / 12 ASP A 230
SER A  55
ARG A  90
GLY A  42
LEU A  43
 GOL  A 248 (-3.7A)
None
None
None
None
 0.78A 3j6pB-3nn2A:
undetectable		 3j6pB-3nn2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		3 / 3 LYS A   1
ARG A  70
VAL A  71
 None
 0.65A 4x3uA-3nn2A:
undetectable
4x3uB-3nn2A:
undetectable		 4x3uA-3nn2A:
13.93
4x3uB-3nn2A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		4 / 4 GLY A  98
ALA A  17
MET A  87
THR A  15
 None
 1.41A 5n0sB-3nn2A:
undetectable		 5n0sB-3nn2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		5 / 12 ASP A 230
LEU A  95
SER A  55
GLY A  42
LEU A  43
 GOL  A 248 (-3.7A)
None
None
None
None
 1.15A 6b0lB-3nn2A:
undetectable		 6b0lB-3nn2A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nn2 CHLORITE DISMUTASE
(Nitrospira
defluvii) 		4 / 5 LEU A 205
GLN A 207
PHE A 211
PHE A 198
 HEM  A 239 (-4.9A)
None
None
None
 1.46A 6nmpP-3nn2A:
undetectable
6nmpW-3nn2A:
undetectable		 6nmpP-3nn2A:
22.74
6nmpW-3nn2A:
19.44