SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nn8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3nn8 ENGINEERED SCFV,
HEAVY CHAIN
(Mus
musculus) 		5 / 10 ASP A  56
ASP A  57
VAL A  73
ILE A  53
GLY A  35
 None
 1.23A 1d4sA-3nn8A:
undetectable		 1d4sA-3nn8A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3nn8 ENGINEERED SCFV,
HEAVY CHAIN
(Mus
musculus) 		5 / 7 SER A   7
LYS A  40
LEU A  50
LEU A  82
THR A 116
 None
 1.27A 3cfqA-3nn8A:
undetectable
3cfqB-3nn8A:
undetectable		 3cfqA-3nn8A:
21.23
3cfqB-3nn8A:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3nn8 ENGINEERED SCFV,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL A   2
TYR A  27
ARG A  99
TYR A 111
 None
 0.31A 4m7kH-3nn8A:
20.5		 4m7kH-3nn8A:
57.48