SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 7 TRP B 278
LEU B 279
THR B 295
LEU B  38
GLY B  41
 None
 1.24A 1gtiA-3nndB:
undetectable		 1gtiA-3nndB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 7 TRP B 278
THR B 295
LEU B  38
GLY B  41
 None
 0.78A 1gtiB-3nndB:
undetectable		 1gtiB-3nndB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 7 TRP B 278
THR B  36
LEU B  38
GLY B  41
 None
 1.01A 1gtiE-3nndB:
undetectable		 1gtiE-3nndB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 7 TRP B 278
THR B 295
LEU B  38
GLY B  41
 None
 0.91A 1gtiE-3nndB:
undetectable		 1gtiE-3nndB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 8 TYR B  79
LEU B  19
LEU B  75
GLU B 113
 None
 0.84A 1i7zA-3nndB:
undetectable		 1i7zA-3nndB:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 7 MET B 324
ALA B 322
ILE B 321
ILE B 109
 None
 0.91A 1upfB-3nndB:
undetectable		 1upfB-3nndB:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 12 ILE B  17
ALA B  18
LEU B 110
ILE B 109
ALA B  78
 None
 0.97A 2aclG-3nndB:
undetectable		 2aclG-3nndB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 10 ILE B 147
PRO B 249
LYS B 149
GLY B 148
LYS B 212
 None
 0.82A 3ik6B-3nndB:
undetectable
3ik6E-3nndB:
undetectable		 3ik6B-3nndB:
20.42
3ik6E-3nndB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 10 LYS B 212
ILE B 147
PRO B 249
LYS B 149
GLY B 148
 None
 0.78A 3ik6B-3nndB:
undetectable
3ik6E-3nndB:
undetectable		 3ik6B-3nndB:
20.42
3ik6E-3nndB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 11 ILE B 147
PRO B 249
LYS B 149
GLY B 148
LYS B 212
 None
 0.83A 3iluB-3nndB:
undetectable
3iluE-3nndB:
undetectable		 3iluB-3nndB:
20.42
3iluE-3nndB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 5 ILE B 147
PRO B 249
LYS B 149
GLY B 148
 None
 0.76A 3tkdB-3nndB:
undetectable		 3tkdB-3nndB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 5 ILE B 147
PRO B 249
LYS B 149
GLY B 148
 None
 0.77A 3tkdA-3nndB:
undetectable		 3tkdA-3nndB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 12 LEU B  75
ILE B 109
ILE B  20
ASP B  85
ALA B  84
 None
 1.38A 3uj7A-3nndB:
undetectable		 3uj7A-3nndB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 6 ALA B  94
ALA B 115
PRO B 114
THR B  90
 None
 0.98A 4dtzA-3nndB:
undetectable		 4dtzA-3nndB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		5 / 12 LYS B 172
PHE B 171
GLY B 164
GLY B 167
THR B 190
 None
 1.11A 5kpcB-3nndB:
undetectable		 5kpcB-3nndB:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 7 THR B  34
PHE B 293
GLN B 138
THR B 132
 None
 1.42A 5u6mA-3nndB:
4.1		 5u6mA-3nndB:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3nnd POSSIBLE SUBSTRATE
BINDING PROTEIN OF
ABC TRANSPORTER
SYSTEM
(Rhodopseudomonas
palustris) 		4 / 6 SER B 300
PHE B 293
GLN B 138
MET B 336
 None
 1.25A 5u6nB-3nndB:
4.0		 5u6nB-3nndB:
22.46