SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		4 / 7 ILE A 331
GLU A 335
LEU A 245
VAL A 312
 None
 0.83A 3ua5B-3nngA:
undetectable		 3ua5B-3nngA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		4 / 7 ILE A 273
LEU A 251
GLY A 253
PHE A 254
 None
 0.93A 4iqqA-3nngA:
undetectable		 4iqqA-3nngA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		5 / 12 ALA A 216
VAL A 201
CYH A 203
LEU A 251
PHE A 328
 None
 1.10A 4qrcA-3nngA:
undetectable		 4qrcA-3nngA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		4 / 7 TYR A 334
VAL A 194
TRP A 199
ILE A 220
 None
 1.25A 4xo7B-3nngA:
undetectable		 4xo7B-3nngA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		3 / 3 GLU A 278
LYS A 313
ASN A 311
 None
 1.06A 4y1dA-3nngA:
undetectable
4y1dD-3nngA:
undetectable		 4y1dA-3nngA:
19.08
4y1dD-3nngA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3nng UNCHARACTERIZED
PROTEIN
(Bacteroides
fragilis) 		3 / 3 TYR A 262
ALA A 208
TYR A 207
 None
 0.85A 5uunB-3nngA:
undetectable		 5uunB-3nngA:
21.03