SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nnk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 335
LEU A 341
ALA A 338
GLU A 344
 None
 0.82A 1dmaA-3nnkA:
undetectable		 1dmaA-3nnkA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 4 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.41A 1fbmD-3nnkA:
undetectable		 1fbmD-3nnkA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 5 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.58A 1fbmE-3nnkA:
undetectable		 1fbmE-3nnkA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 6 ALA A 293
LYS A 296
ASP A 300
ALA A 301
 None
 0.42A 1iwhA-3nnkA:
undetectable		 1iwhA-3nnkA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 4 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.92A 1mz9D-3nnkA:
undetectable		 1mz9D-3nnkA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 8 PHE A  99
ILE A  80
ILE A  77
THR A 176
 LLP  A 200 ( 3.7A)
None
None
LLP  A 200 ( 3.3A)
 0.94A 1sbrA-3nnkA:
undetectable		 1sbrA-3nnkA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 PHE A  99
ILE A  80
ILE A  77
THR A 176
 LLP  A 200 ( 3.7A)
None
None
LLP  A 200 ( 3.3A)
 0.92A 1sbrB-3nnkA:
2.5		 1sbrB-3nnkA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 GLY A 299
ASP A 300
ASN A 323
 None
 0.56A 1vq1A-3nnkA:
4.1		 1vq1A-3nnkA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 326
SER A 150
SER A 353
PHE A 314
 None
 0.93A 2c8aB-3nnkA:
undetectable		 2c8aB-3nnkA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 326
SER A 150
SER A 353
PHE A 314
 None
 0.94A 2c8aD-3nnkA:
undetectable		 2c8aD-3nnkA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 184
LEU A 157
LEU A 160
LEU A  92
VAL A 134
 None
 0.93A 2pnjA-3nnkA:
2.7		 2pnjA-3nnkA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		6 / 12 ALA A 371
GLY A 180
HIS A 295
GLY A 203
ILE A  22
LEU A 179
 None
None
None
LLP  A 200 ( 4.9A)
LLP  A 200 ( 4.1A)
None
 1.46A 2x1lB-3nnkA:
undetectable		 2x1lB-3nnkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 8 VAL A 130
VAL A 124
PHE A  96
THR A 144
 None
 0.99A 3fhxB-3nnkA:
undetectable		 3fhxB-3nnkA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 CYH A 375
THR A 378
THR A 379
ILE A  22
LEU A 302
 None
None
None
LLP  A 200 ( 4.1A)
None
 1.06A 3gwxA-3nnkA:
undetectable		 3gwxA-3nnkA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 8 SER A  83
ASP A  89
ASP A 250
ASP A 238
 None
 1.15A 3havA-3nnkA:
undetectable		 3havA-3nnkA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 VAL A  51
TYR A  55
TRP A 258
PRO A 210
 None
 1.15A 3hs4A-3nnkA:
undetectable		 3hs4A-3nnkA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 GLU A 105
HIS A 101
VAL A 114
ALA A 107
 None
 1.00A 3kp6B-3nnkA:
undetectable		 3kp6B-3nnkA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 11 GLY A 305
LEU A 311
LEU A 325
LEU A 383
LEU A 380
 None
 1.40A 3ndvA-3nnkA:
undetectable
3ndvB-3nnkA:
undetectable		 3ndvA-3nnkA:
26.07
3ndvB-3nnkA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A 160
LEU A 103
PRO A  94
LEU A 143
 None
 0.98A 3q1eA-3nnkA:
undetectable
3q1eC-3nnkA:
undetectable		 3q1eA-3nnkA:
14.32
3q1eC-3nnkA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 CYH A 104
HIS A 101
THR A 151
SER A 150
VAL A 145
 None
None
None
None
LLP  A 200 ( 4.8A)
 1.37A 3u9fP-3nnkA:
undetectable
3u9fS-3nnkA:
undetectable		 3u9fP-3nnkA:
18.18
3u9fS-3nnkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 4 PRO A  94
LEU A  92
ILE A 137
ARG A 138
 None
 1.18A 3w1wA-3nnkA:
undetectable		 3w1wA-3nnkA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 122
ASP A 316
GLY A 315
VAL A 124
 None
 0.87A 4c5nA-3nnkA:
5.3		 4c5nA-3nnkA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 THR A 208
LEU A  68
VAL A  51
VAL A  28
 None
 1.07A 4l4gA-3nnkA:
undetectable		 4l4gA-3nnkA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 173
THR A 144
PHE A  99
 None
None
LLP  A 200 ( 3.7A)
 0.82A 5cxvA-3nnkA:
undetectable		 5cxvA-3nnkA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 233
ASP A 234
ALA A 235
 None
 0.07A 5g5gB-3nnkA:
undetectable		 5g5gB-3nnkA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 MET A  32
THR A 271
LEU A 273
ALA A 269
GLU A 268
 None
 0.91A 5gs4A-3nnkA:
undetectable		 5gs4A-3nnkA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 147
ALA A 175
PHE A 171
LEU A 179
VAL A 194
 None
 1.19A 5hw4A-3nnkA:
1.8		 5hw4A-3nnkA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 11 GLY A 147
ALA A 175
PHE A 171
LEU A 179
VAL A 194
 None
 1.20A 5hw4B-3nnkA:
1.8		 5hw4B-3nnkA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 147
ALA A 175
PHE A 171
LEU A 179
VAL A 194
 None
 1.21A 5hw4C-3nnkA:
undetectable		 5hw4C-3nnkA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 CYH A 375
LYS A 373
HIS A 298
 None
 1.09A 5js5A-3nnkA:
undetectable		 5js5A-3nnkA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 HIS A  46
ASN A  49
ALA A  53
 None
 0.14A 5n4tB-3nnkA:
2.0		 5n4tB-3nnkA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 144
PRO A 139
ARG A 140
 None
 0.83A 5nd7B-3nnkA:
undetectable		 5nd7B-3nnkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 7 THR A 208
LEU A  68
VAL A  51
VAL A  28
 None
 1.04A 5wk9A-3nnkA:
undetectable		 5wk9A-3nnkA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 9 LEU A 383
THR A 379
ILE A 364
VAL A 327
ILE A 306
 None
 1.28A 6ef6A-3nnkA:
undetectable		 6ef6A-3nnkA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 11 THR A  61
PHE A  59
ALA A 196
LEU A 251
ALA A  84
 None
 1.04A 6efnA-3nnkA:
2.0		 6efnA-3nnkA:
22.17