SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3nnm CURA
(Lyngbya
majuscula) 		4 / 7 TYR A 209
ASP A 202
GLU A 198
TRP A 114
 None
 1.41A 1b2iA-3nnmA:
undetectable		 1b2iA-3nnmA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 ASN A 223
PHE A 220
VAL A 226
 None
 0.78A 1kijA-3nnmA:
undetectable		 1kijA-3nnmA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 ASP A 128
ASP A 256
LYS A 224
 None
 1.16A 1lqtB-3nnmA:
undetectable		 1lqtB-3nnmA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 ASP A 128
ASP A 256
LYS A 224
 None
 1.15A 1lquB-3nnmA:
undetectable		 1lquB-3nnmA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 GLY A 130
LEU A  95
MET A  96
PHE A 123
HIS A  99
 None
None
None
None
FMT  A 750 (-4.3A)
 1.07A 1mx1F-3nnmA:
undetectable		 1mx1F-3nnmA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 ASP A 166
LEU A 169
HIS A  99
 None
None
FMT  A 750 (-4.3A)
 0.69A 1qknA-3nnmA:
undetectable		 1qknA-3nnmA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 HIS A  66
ALA A  67
LEU A 102
ALA A 101
GLN A 229
 None
None
None
FMT  A 750 ( 4.0A)
None
 1.28A 2jjpA-3nnmA:
undetectable		 2jjpA-3nnmA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 GLU A  49
HIS A 270
THR A 276
 None
 0.47A 3hkuA-3nnmA:
undetectable		 3hkuA-3nnmA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 8 LYS A  54
HIS A  99
ASP A 166
LEU A 169
 FMT  A 750 ( 4.8A)
FMT  A 750 (-4.3A)
None
None
 1.07A 3n2oC-3nnmA:
undetectable
3n2oD-3nnmA:
undetectable		 3n2oC-3nnmA:
20.00
3n2oD-3nnmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 TYR A 150
ASP A 218
ASP A 212
 None
 0.61A 3r24A-3nnmA:
undetectable		 3r24A-3nnmA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3nnm CURA
(Lyngbya
majuscula) 		3 / 3 TYR A 225
LEU A   9
LYS A  10
 FMT  A 754 (-4.2A)
None
None
 0.78A 3sueD-3nnmA:
0.0		 3sueD-3nnmA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 LEU A 112
ILE A  61
ILE A  58
ARG A 259
HIS A 115
 FMT  A 500 ( 4.8A)
None
None
None
None
 1.36A 3uj7A-3nnmA:
undetectable		 3uj7A-3nnmA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 PHE A 103
LEU A 102
ALA A 101
GLY A 117
LEU A  55
 FMT  A 500 (-4.9A)
None
FMT  A 750 ( 4.0A)
None
None
 0.89A 4dm8B-3nnmA:
undetectable		 4dm8B-3nnmA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 LEU A 102
ALA A 219
PHE A  79
PHE A  25
VAL A  76
 None
 1.23A 4ib4A-3nnmA:
undetectable		 4ib4A-3nnmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 6 THR A 191
LEU A 262
GLN A 268
LEU A 269
 None
 1.20A 4nc3A-3nnmA:
undetectable		 4nc3A-3nnmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 6 ILE A  61
ASP A  60
GLY A  56
VAL A 186
 None
FMT  A 755 (-4.2A)
None
None
 1.00A 4oltA-3nnmA:
undetectable		 4oltA-3nnmA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 6 ILE A  61
ASP A  60
GLY A  56
VAL A 186
 None
FMT  A 755 (-4.2A)
None
None
 1.01A 4oltB-3nnmA:
undetectable		 4oltB-3nnmA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 6 ASP A  59
TYR A 193
TYR A 266
LEU A 169
 None
 1.38A 5bmvB-3nnmA:
undetectable		 5bmvB-3nnmA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 GLU A  43
LEU A  37
ALA A 101
ASN A 100
VAL A  76
 None
None
FMT  A 750 ( 4.0A)
None
None
 1.31A 5kbwB-3nnmA:
undetectable		 5kbwB-3nnmA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 10 ILE A  80
PHE A  25
LEU A 102
ALA A 243
LEU A 137
 None
None
None
FMT  A 500 (-3.6A)
None
 0.96A 5y7pB-3nnmA:
undetectable		 5y7pB-3nnmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 10 ILE A  80
PHE A  25
LEU A 102
ALA A 243
LEU A 137
 None
None
None
FMT  A 500 (-3.6A)
None
 1.00A 5y7pD-3nnmA:
undetectable		 5y7pD-3nnmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 10 ILE A  80
PHE A  25
LEU A 102
ALA A 243
LEU A 137
 None
None
None
FMT  A 500 (-3.6A)
None
 0.99A 5y7pH-3nnmA:
undetectable		 5y7pH-3nnmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 7 VAL A 226
PHE A 221
MET A  98
LEU A  95
 None
 1.19A 6aycA-3nnmA:
undetectable		 6aycA-3nnmA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 ILE A 135
VAL A  76
LEU A 137
PHE A  25
THR A  36
 None
 1.24A 6b52A-3nnmA:
undetectable		 6b52A-3nnmA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3nnm CURA
(Lyngbya
majuscula) 		5 / 12 ILE A 135
VAL A  76
PHE A  25
LEU A  37
THR A  36
 None
 1.19A 6b52A-3nnmA:
undetectable		 6b52A-3nnmA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3nnm CURA
(Lyngbya
majuscula) 		4 / 7 HIS A 168
THR A 191
ARG A 259
ASP A 166
 None
 1.28A 6mn4E-3nnmA:
undetectable		 6mn4E-3nnmA:
20.00