SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE
(Murine
leukemia
virus) 		4 / 7 GLN A  48
GLU A  52
MET A  45
MET A  81
 None
 1.35A 1linA-3nnqA:
undetectable		 1linA-3nnqA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE
(Murine
leukemia
virus) 		4 / 5 LEU A  88
CYH A  95
ALA A  97
CYH A  98
 None
ZN  A 201 (-2.2A)
ZN  A 201 ( 4.4A)
ZN  A 201 (-2.3A)
 0.72A 1mz9D-3nnqA:
undetectable		 1mz9D-3nnqA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE
(Murine
leukemia
virus) 		4 / 5 ASP A  85
LEU A  88
MET A  68
ARG A  84
 None
 1.42A 2gj5A-3nnqA:
undetectable		 2gj5A-3nnqA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE
(Murine
leukemia
virus) 		4 / 7 TYR A  80
GLU A  73
LEU A  82
ASN A  83
 None
 1.27A 3k8mA-3nnqA:
undetectable		 3k8mA-3nnqA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE
(Murine
leukemia
virus) 		3 / 3 ALA A  28
TRP A  37
VAL A  38
 None
 0.23A 4w9nC-3nnqA:
undetectable		 4w9nC-3nnqA:
14.87