SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nnr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 PHE A  45
LEU A  34
SER A  13
 None
 0.94A 1e7aA-3nnrA:
4.0		 1e7aA-3nnrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 VAL A 157
VAL A  87
ILE A 126
ARG A 209
 None
UNL  A 230 ( 4.7A)
UNL  A 230 ( 4.9A)
None
 1.04A 1iepA-3nnrA:
undetectable		 1iepA-3nnrA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLU A 193
LEU A 133
MET A  80
LEU A  84
 None
None
UNL  A 230 ( 4.3A)
UNL  A 230 ( 4.9A)
 1.11A 1linA-3nnrA:
undetectable		 1linA-3nnrA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 LEU A  84
SER A  86
PHE A  88
ILE A 158
 UNL  A 230 ( 4.9A)
None
None
UNL  A 230 ( 4.6A)
 0.95A 3ko0B-3nnrA:
undetectable		 3ko0B-3nnrA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 VAL A 157
VAL A  87
ILE A 126
ARG A 209
 None
UNL  A 230 ( 4.7A)
UNL  A 230 ( 4.9A)
None
 1.06A 3mssB-3nnrA:
undetectable		 3mssB-3nnrA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 ASP A  64
HIS A  98
VAL A  63
VAL A  87
THR A 159
 None
UNL  A 230 ( 4.2A)
None
UNL  A 230 ( 4.7A)
None
 1.30A 4yhaC-3nnrA:
undetectable		 4yhaC-3nnrA:
21.46