SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3no0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3no0 DNA GYRASE SUBUNIT A
(Aquifex
aeolicus) 		5 / 11 GLY A 704
THR A 705
GLU A 701
LEU A 712
GLY A 630
 None
 1.06A 1i7qA-3no0A:
undetectable		 1i7qA-3no0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3no0 DNA GYRASE SUBUNIT A
(Aquifex
aeolicus) 		5 / 12 ALA A 730
LEU A 512
SER A 505
ILE A 506
LEU A 531
 None
 1.06A 4ky8C-3no0A:
undetectable		 4ky8C-3no0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 3no0 DNA GYRASE SUBUNIT A
(Aquifex
aeolicus) 		5 / 11 ILE A 765
LEU A 712
GLY A 663
SER A 613
ALA A 615
 None
None
GOL  A   1 (-3.2A)
GOL  A   1 (-3.3A)
GOL  A   1 ( 4.2A)
 1.35A 6ieyA-3no0A:
undetectable
6ieyB-3no0A:
undetectable		 6ieyA-3no0A:
21.43
6ieyB-3no0A:
21.43