SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3no3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 ILE A  28
VAL A  72
ASN A  42
GLY A  57
 None
 0.84A 1dzmA-3no3A:
undetectable		 1dzmA-3no3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 6 HIS A  63
LEU A  91
LEU A 102
PRO A 103
 None
 0.91A 1hz4A-3no3A:
undetectable		 1hz4A-3no3A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 LEU A 149
VAL A 144
VAL A  72
VAL A  62
 None
 0.96A 1iwiA-3no3A:
undetectable		 1iwiA-3no3A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 144
PHE A 122
LEU A  47
VAL A  62
LEU A  70
 None
 1.25A 2jn3A-3no3A:
undetectable		 2jn3A-3no3A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 SER A 176
ILE A 156
ASP A 154
ARG A 119
 None
 1.01A 2v57A-3no3A:
undetectable		 2v57A-3no3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 SER A 176
ILE A 156
ASP A 154
ARG A 119
 None
 1.02A 2v57C-3no3A:
undetectable		 2v57C-3no3A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		3 / 3 GLU A 123
HIS A  30
GLU A  59
 MG  A 301 ( 2.8A)
GOL  A 303 (-3.8A)
MG  A 301 ( 2.6A)
 0.77A 2x45B-3no3A:
undetectable		 2x45B-3no3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		3 / 3 GLU A 123
HIS A  30
GLU A  59
 MG  A 301 ( 2.8A)
GOL  A 303 (-3.8A)
MG  A 301 ( 2.6A)
 0.78A 2x45C-3no3A:
undetectable		 2x45C-3no3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 SER A 126
GLU A 123
GLU A  59
TRP A 222
 None
MG  A 301 ( 2.8A)
MG  A 301 ( 2.6A)
GOL  A 303 ( 3.8A)
 1.15A 3sg9B-3no3A:
undetectable		 3sg9B-3no3A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 6 GLU A  59
ILE A 156
GLU A 181
VAL A 201
 MG  A 301 ( 2.6A)
None
None
None
 0.95A 4ejwB-3no3A:
undetectable		 4ejwB-3no3A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 ASP A  61
ASP A 244
ASN A  42
GLU A 123
 MG  A 301 (-2.5A)
None
None
MG  A 301 ( 2.8A)
 1.20A 4fevB-3no3A:
undetectable		 4fevB-3no3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 ASP A  61
ASP A 244
ASN A  42
GLU A 123
 MG  A 301 (-2.5A)
None
None
MG  A 301 ( 2.8A)
 1.21A 4fewB-3no3A:
undetectable		 4fewB-3no3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 ASP A  61
ASP A 244
ASN A  42
GLU A 123
 MG  A 301 (-2.5A)
None
None
MG  A 301 ( 2.8A)
 1.20A 4gkhD-3no3A:
undetectable		 4gkhD-3no3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 6 ASP A  61
ASP A 244
ASN A  42
GLU A 123
 MG  A 301 (-2.5A)
None
None
MG  A 301 ( 2.8A)
 1.20A 4gkhJ-3no3A:
undetectable		 4gkhJ-3no3A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 120
LEU A 109
ALA A 112
LEU A  47
VAL A  62
 None
 1.06A 4p65C-3no3A:
undetectable
4p65D-3no3A:
undetectable
4p65J-3no3A:
undetectable
4p65L-3no3A:
undetectable		 4p65C-3no3A:
8.18
4p65D-3no3A:
7.98
4p65J-3no3A:
7.98
4p65L-3no3A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		5 / 11 LEU A  47
VAL A  62
LEU A 120
LEU A 109
ALA A 112
 None
 1.14A 4p65B-3no3A:
undetectable
4p65D-3no3A:
undetectable
4p65G-3no3A:
undetectable
4p65H-3no3A:
undetectable		 4p65B-3no3A:
7.98
4p65D-3no3A:
7.98
4p65G-3no3A:
8.18
4p65H-3no3A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 GLU A  48
LEU A  96
ASN A  98
SER A  58
 None
 1.09A 4pfjA-3no3A:
undetectable		 4pfjA-3no3A:
20.50