SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3no5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 HIS A  49
GLY A  85
GLY A  86
TYR A 119
 ZN  A 275 (-3.3A)
None
None
None
 0.72A 1ekjA-3no5A:
undetectable
1ekjB-3no5A:
undetectable		 1ekjA-3no5A:
20.22
1ekjB-3no5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 HIS A  49
GLY A  85
GLY A  86
TYR A 119
 ZN  A 275 (-3.3A)
None
None
None
 0.66A 1ekjE-3no5A:
undetectable
1ekjF-3no5A:
undetectable		 1ekjE-3no5A:
20.22
1ekjF-3no5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 HIS A  49
GLY A  85
GLY A  86
TYR A 119
 ZN  A 275 (-3.3A)
None
None
None
 0.67A 1ekjG-3no5A:
undetectable
1ekjH-3no5A:
undetectable		 1ekjG-3no5A:
20.22
1ekjH-3no5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 HIS A  49
SER A  14
TYR A 119
PHE A 114
 ZN  A 275 (-3.3A)
None
None
None
 1.21A 1eqbA-3no5A:
undetectable
1eqbB-3no5A:
undetectable		 1eqbA-3no5A:
21.77
1eqbB-3no5A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A 119
PHE A 114
HIS A  49
SER A  14
 None
None
ZN  A 275 (-3.3A)
None
 1.22A 1eqbA-3no5A:
undetectable
1eqbB-3no5A:
undetectable		 1eqbA-3no5A:
21.77
1eqbB-3no5A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 HIS A  49
SER A  14
TYR A 119
PHE A 114
 ZN  A 275 (-3.3A)
None
None
None
 1.21A 1eqbC-3no5A:
undetectable
1eqbD-3no5A:
undetectable		 1eqbC-3no5A:
21.77
1eqbD-3no5A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A 119
PHE A 114
HIS A  49
SER A  14
 None
None
ZN  A 275 (-3.3A)
None
 1.23A 1eqbC-3no5A:
undetectable
1eqbD-3no5A:
undetectable		 1eqbC-3no5A:
21.77
1eqbD-3no5A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 10 THR A 226
HIS A  47
ALA A  43
ASN A 243
ALA A  38
 None
ZN  A 275 (-3.3A)
None
None
None
 0.94A 1likA-3no5A:
2.1		 1likA-3no5A:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 GLU A 229
HIS A  47
HIS A  49
 ZN  A 275 (-2.6A)
ZN  A 275 (-3.3A)
ZN  A 275 (-3.3A)
 0.70A 1oe2A-3no5A:
undetectable		 1oe2A-3no5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 4 GLY A  95
SER A  59
VAL A  82
LEU A 129
 None
 1.20A 1yajB-3no5A:
undetectable		 1yajB-3no5A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 TRP A 128
THR A 135
TYR A 136
 None
 1.05A 2a3aA-3no5A:
7.6		 2a3aA-3no5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 TRP A 128
THR A 135
TYR A 136
 None
 0.96A 2a3aB-3no5A:
7.0		 2a3aB-3no5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 TRP A 128
THR A 135
TYR A 136
 None
 1.05A 2a3bA-3no5A:
4.8		 2a3bA-3no5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A 119
HIS A  49
GLU A 229
HIS A  47
 None
ZN  A 275 (-3.3A)
ZN  A 275 (-2.6A)
ZN  A 275 (-3.3A)
 0.97A 2bnnA-3no5A:
undetectable
2bnnB-3no5A:
undetectable		 2bnnA-3no5A:
24.13
2bnnB-3no5A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 5 GLY A  85
GLY A  86
PHE A 145
PHE A 114
 None
 1.07A 2qr2A-3no5A:
undetectable
2qr2B-3no5A:
undetectable		 2qr2A-3no5A:
24.33
2qr2B-3no5A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A 215
VAL A 247
THR A 226
 None
 0.83A 3cyxA-3no5A:
undetectable		 3cyxA-3no5A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 PRO A 165
LEU A 166
GLN A 157
 None
 0.44A 3hznG-3no5A:
undetectable
3hznH-3no5A:
undetectable		 3hznG-3no5A:
25.35
3hznH-3no5A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A 204
HIS A  49
HIS A  47
ASP A 230
ILE A 174
 None
ZN  A 275 (-3.3A)
ZN  A 275 (-3.3A)
None
None
 1.36A 3njzA-3no5A:
undetectable		 3njzA-3no5A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 5 GLN A  81
HIS A  47
GLU A 143
PHE A 145
 None
ZN  A 275 (-3.3A)
None
None
 1.34A 3py4A-3no5A:
undetectable		 3py4A-3no5A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 GLN A  81
HIS A  47
GLU A 143
PHE A 145
 None
ZN  A 275 (-3.3A)
None
None
 1.35A 3ql6A-3no5A:
undetectable		 3ql6A-3no5A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 6 ARG A  51
ASP A 230
GLN A 210
GLU A 141
 None
 1.45A 4azvA-3no5A:
undetectable		 4azvA-3no5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 ALA A 264
ALA A  43
ALA A  75
PRO A  76
 None
 0.75A 4du2B-3no5A:
undetectable		 4du2B-3no5A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 7 ILE A 150
HIS A 167
LEU A 166
ALA A 199
 None
 0.96A 5hrqE-3no5A:
undetectable
5hrqF-3no5A:
undetectable
5hrqJ-3no5A:
undetectable		 5hrqE-3no5A:
7.33
5hrqF-3no5A:
9.45
5hrqJ-3no5A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 203
THR A 202
CYH A 224
ALA A 214
LEU A 211
 None
 1.19A 5hw4A-3no5A:
undetectable		 5hw4A-3no5A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 203
THR A 202
CYH A 224
ALA A 214
LEU A 211
 None
 1.20A 5hw4C-3no5A:
undetectable		 5hw4C-3no5A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 GLY A 227
LEU A 246
GLN A 210
ALA A 214
 None
 0.86A 5xu8A-3no5A:
undetectable		 5xu8A-3no5A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 3no5 UNCHARACTERIZED
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 5 HIS A  49
SER A  83
GLY A  85
TYR A 119
 ZN  A 275 (-3.3A)
ZN  A 275 ( 3.9A)
None
None
 1.22A 5yodD-3no5A:
undetectable		 5yodD-3no5A:
24.82