SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3no6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		5 / 9 TYR A  40
ASP A  44
LEU A  89
ILE A 144
PHE A 212
 None
IMD  A 300 (-3.3A)
None
None
None
 1.33A 1q6iA-3no6A:
undetectable		 1q6iA-3no6A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		4 / 4 LEU A  89
ILE A  18
ARG A 209
TYR A 167
 None
 1.49A 1rk3A-3no6A:
2.7		 1rk3A-3no6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.75A 2dysN-3no6A:
2.3		 2dysN-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		4 / 7 PHE A   3
LEU A 202
PRO A 136
ALA A 132
 None
 0.99A 2vcvG-3no6A:
undetectable		 2vcvG-3no6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		4 / 5 LEU A  89
ILE A  18
ARG A 209
TYR A 167
 None
 1.47A 2zlcA-3no6A:
2.8		 2zlcA-3no6A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.78A 3ablN-3no6A:
undetectable		 3ablN-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.76A 3abmN-3no6A:
undetectable		 3abmN-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.76A 3asoA-3no6A:
undetectable		 3asoA-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		5 / 10 TYR A  40
ASP A  44
LEU A  89
ILE A 144
PHE A 212
 None
IMD  A 300 (-3.3A)
None
None
None
 1.31A 3kz7A-3no6A:
undetectable		 3kz7A-3no6A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		5 / 10 TYR A  40
VAL A 140
ILE A 144
TRP A 163
LEU A  32
 None
 1.50A 4jtqA-3no6A:
undetectable		 4jtqA-3no6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.78A 5z84A-3no6A:
1.4		 5z84A-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.75A 5z86A-3no6A:
undetectable		 5z86A-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.78A 5z86N-3no6A:
undetectable		 5z86N-3no6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		5 / 12 VAL A 143
ARG A 209
ILE A  15
ASP A  17
ASP A  16
 None
 1.38A 6bxnA-3no6A:
undetectable		 6bxnA-3no6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3no6 TRANSCRIPTIONAL
ACTIVATOR TENA
(Staphylococcus
epidermidis) 		3 / 3 HIS A 116
HIS A 207
HIS A 112
 None
 0.76A 6nmpA-3no6A:
undetectable		 6nmpA-3no6A:
18.48