SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		4 / 7 PRO D  50
ALA D  42
LEU D  18
ALA D  38
 None
 1.08A 2vcvA-3nogD:
undetectable		 2vcvA-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		4 / 6 LEU D 126
ALA D 120
LEU D 117
ALA D 149
 None
 0.99A 2vcvB-3nogD:
undetectable		 2vcvB-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		5 / 9 LEU D 126
LEU D 133
ALA D 120
LEU D 117
ALA D 149
 None
 1.10A 2vcvD-3nogD:
undetectable		 2vcvD-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		5 / 9 LEU D 126
LEU D 133
ALA D 120
LEU D 117
ALA D 149
 None
 1.13A 2vcvE-3nogD:
undetectable		 2vcvE-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		5 / 9 LEU D 126
LEU D 133
ALA D 120
LEU D 117
ALA D 149
 None
 1.14A 2vcvH-3nogD:
undetectable		 2vcvH-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		5 / 9 LEU D 126
LEU D 133
ALA D 120
LEU D 117
ALA D 149
 None
 1.06A 2vcvI-3nogD:
undetectable		 2vcvI-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		4 / 6 LEU D 126
ALA D 120
LEU D 117
ALA D 149
 None
 0.98A 2vcvK-3nogD:
undetectable		 2vcvK-3nogD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		4 / 6 ASP D  77
GLY D  47
VAL D  46
THR D  49
 None
 1.22A 3vqrA-3nogD:
undetectable		 3vqrA-3nogD:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		4 / 5 ASP D  77
GLY D  47
VAL D  46
THR D  49
 None
 1.23A 3vqrB-3nogD:
undetectable		 3vqrB-3nogD:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3nog DESIGNED ANKYRIN
REPEAT PROTEIN
(synthetic
construct) 		3 / 3 ASP D  77
ASP D  89
ASN D 156
 None
 0.73A 6gngB-3nogD:
undetectable		 6gngB-3nogD:
15.87