SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3noj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 12 ARG A 138
GLY A 121
PRO A  91
VAL A  66
PHE A  74
 None
 1.23A 1gseA-3nojA:
undetectable		 1gseA-3nojA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		4 / 4 VAL A 179
ASP A 119
LEU A  65
ARG A 181
 None
 1.48A 2ziaA-3nojA:
undetectable		 2ziaA-3nojA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		4 / 7 ILE A 164
THR A  63
SER A  90
ASP A 173
 None
 1.29A 4iarA-3nojA:
undetectable		 4iarA-3nojA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 9 PHE A  74
ALA A  77
VAL A  86
LEU A 116
VAL A  88
 None
 1.42A 4z69A-3nojA:
undetectable		 4z69A-3nojA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		3 / 3 VAL A  88
GLN A 162
CYH A 159
 None
 0.54A 5icxA-3nojA:
undetectable
5icxE-3nojA:
undetectable		 5icxA-3nojA:
19.18
5icxE-3nojA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		3 / 3 VAL A  88
GLN A 162
CYH A 159
 None
 0.86A 5icxC-3nojA:
undetectable
5icxF-3nojA:
undetectable		 5icxC-3nojA:
19.18
5icxF-3nojA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A  20
VAL A 180
ALA A  25
LEU A  26
ALA A 192
 None
 0.91A 5kpcA-3nojA:
undetectable		 5kpcA-3nojA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 11 THR A 145
VAL A  66
GLY A  98
GLY A 121
ALA A 120
 None
 0.89A 5lf7K-3nojA:
undetectable
5lf7L-3nojA:
undetectable		 5lf7K-3nojA:
24.50
5lf7L-3nojA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 11 THR A 145
VAL A  66
GLY A  98
GLY A 121
ALA A 120
 None
 0.90A 5lf7Y-3nojA:
undetectable
5lf7Z-3nojA:
undetectable		 5lf7Y-3nojA:
24.50
5lf7Z-3nojA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A 115
VAL A 170
ALA A  58
VAL A 177
GLY A  27
 None
 1.22A 6bklA-3nojA:
undetectable
6bklB-3nojA:
undetectable
6bklC-3nojA:
undetectable
6bklD-3nojA:
undetectable		 6bklA-3nojA:
8.07
6bklB-3nojA:
8.07
6bklC-3nojA:
8.07
6bklD-3nojA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		4 / 6 VAL A 153
ASN A 154
PRO A 166
ILE A  15
 None
 1.07A 6h7uA-3nojA:
undetectable		 6h7uA-3nojA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE
(Pseudomonas
putida) 		4 / 8 VAL A 153
ASN A 154
PRO A 166
ILE A  15
 None
 1.04A 6hzpA-3nojA:
undetectable		 6hzpA-3nojA:
19.15