SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		5 / 12 LEU A 174
ASP A 190
ILE A 205
GLY A 203
VAL A 202
 None
 1.14A 2o4lA-3nokA:
undetectable		 2o4lA-3nokA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 8 LEU A  96
ARG A  66
LEU A  68
GLY A 227
 None
 0.95A 2po5B-3nokA:
undetectable		 2po5B-3nokA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		5 / 12 LEU A 174
ILE A 228
VAL A 201
VAL A 161
PRO A 196
 None
 1.11A 2ygpA-3nokA:
undetectable		 2ygpA-3nokA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		3 / 3 GLY A 128
GLY A  47
GLY A  88
 None
 0.36A 3bogC-3nokA:
undetectable		 3bogC-3nokA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		3 / 3 GLY A 128
GLY A  47
GLY A  88
 None
 0.30A 3bogD-3nokA:
undetectable		 3bogD-3nokA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 5 GLN A  98
THR A 240
HIS A  39
LEU A  68
 None
 1.24A 3ce6C-3nokA:
undetectable		 3ce6C-3nokA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.48A 3jt3A-3nokA:
undetectable
3jt3B-3nokA:
undetectable		 3jt3A-3nokA:
21.04
3jt3B-3nokA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.50A 3n5vA-3nokA:
undetectable
3n5vB-3nokA:
undetectable		 3n5vA-3nokA:
21.04
3n5vB-3nokA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.46A 3nloA-3nokA:
undetectable
3nloB-3nokA:
undetectable		 3nloA-3nokA:
20.86
3nloB-3nokA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		5 / 12 GLY A 227
ARG A  80
GLY A  88
ARG A  66
THR A  59
 None
 0.97A 3sugA-3nokA:
undetectable		 3sugA-3nokA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 ARG A 236
VAL A 250
PHE A 238
GLU A  36
 None
 1.47A 3tylA-3nokA:
undetectable
3tylB-3nokA:
undetectable		 3tylA-3nokA:
21.04
3tylB-3nokA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.48A 3tynA-3nokA:
undetectable
3tynB-3nokA:
undetectable		 3tynA-3nokA:
21.04
3tynB-3nokA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		5 / 12 ILE A 181
ILE A 237
VAL A 250
ASN A 184
ASN A 226
 None
 1.00A 4a81A-3nokA:
undetectable		 4a81A-3nokA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.48A 4d30A-3nokA:
undetectable
4d30B-3nokA:
undetectable		 4d30A-3nokA:
21.04
4d30B-3nokA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 6 GLU A 231
THR A 240
HIS A  39
LEU A  70
 None
 0.90A 4pgfA-3nokA:
undetectable		 4pgfA-3nokA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		4 / 7 PHE A 238
GLU A  36
ARG A 236
VAL A 250
 None
 1.42A 5fvuA-3nokA:
undetectable
5fvuB-3nokA:
undetectable		 5fvuA-3nokA:
21.35
5fvuB-3nokA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3nok GLUTAMINYL CYCLASE
(Myxococcus
xanthus) 		3 / 3 ARG A 121
GLY A 104
GLU A 103
 None
 0.55A 6fgdA-3nokA:
undetectable		 6fgdA-3nokA:
21.12