SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3noq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		4 / 6 GLY A  70
ASP A  17
GLY A 151
SER A  99
 NHE  A 501 ( 4.7A)
EDO  A 604 ( 4.6A)
None
None
 0.78A 1eswA-3noqA:
undetectable		 1eswA-3noqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A  73
GLY A  71
GLY A  70
PRO A  69
ASP A  80
 None
NHE  A 501 (-2.7A)
NHE  A 501 ( 4.7A)
None
None
 1.19A 1qzzA-3noqA:
3.3		 1qzzA-3noqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 10 LEU A 107
ALA A  94
ALA A  91
VAL A 106
LEU A   8
 None
 1.04A 1rlbE-3noqA:
undetectable		 1rlbE-3noqA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A  73
GLY A  71
GLY A  70
ASP A  80
SER A  46
 None
NHE  A 501 (-2.7A)
NHE  A 501 ( 4.7A)
None
None
 0.91A 1xdsA-3noqA:
3.0		 1xdsA-3noqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A  73
GLY A  71
GLY A  70
ASP A  80
SER A  46
 None
NHE  A 501 (-2.7A)
NHE  A 501 ( 4.7A)
None
None
 0.91A 1xdsB-3noqA:
3.1		 1xdsB-3noqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A  73
GLY A  71
GLY A  70
PRO A  69
ASP A  80
 None
NHE  A 501 (-2.7A)
NHE  A 501 ( 4.7A)
None
None
 1.17A 1xdsB-3noqA:
3.1		 1xdsB-3noqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		3 / 3 PRO A 196
THR A 194
PRO A 192
 None
 0.85A 2d55C-3noqA:
undetectable		 2d55C-3noqA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		3 / 3 LEU A 131
PRO A 130
ARG A 220
 None
 0.59A 2qd4B-3noqA:
2.4		 2qd4B-3noqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 ALA A 207
THR A 102
SER A 101
LEU A 128
PRO A 135
 NHE  A 501 (-3.8A)
NHE  A 501 ( 2.7A)
EDO  A 604 ( 4.2A)
None
None
 1.16A 3cl9A-3noqA:
undetectable		 3cl9A-3noqA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 10 THR A 120
LEU A 128
LEU A 131
GLY A 108
VAL A  74
 None
 1.23A 3lxiA-3noqA:
undetectable		 3lxiA-3noqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 10 THR A 120
LEU A 128
LEU A 131
GLY A 108
VAL A  74
 None
 1.24A 4c9nB-3noqA:
undetectable		 4c9nB-3noqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 9 THR A 120
LEU A 128
LEU A 131
GLY A 108
VAL A  74
 None
 1.26A 4c9pA-3noqA:
undetectable		 4c9pA-3noqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A 150
GLY A 151
ALA A 123
GLY A  70
ASP A  17
 None
None
NHE  A 501 ( 4.4A)
NHE  A 501 ( 4.7A)
EDO  A 604 ( 4.6A)
 0.86A 4n09B-3noqA:
4.7		 4n09B-3noqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A 150
GLY A 151
ALA A 123
GLY A  70
ASP A  17
 None
None
NHE  A 501 ( 4.4A)
NHE  A 501 ( 4.7A)
EDO  A 604 ( 4.6A)
 0.83A 4n09C-3noqA:
4.4		 4n09C-3noqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 GLY A 150
GLY A 151
ALA A 123
GLY A  70
ASP A  17
 None
None
NHE  A 501 ( 4.4A)
NHE  A 501 ( 4.7A)
EDO  A 604 ( 4.6A)
 0.84A 4n09D-3noqA:
4.6		 4n09D-3noqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 LEU A 146
ALA A  91
GLY A 111
ALA A 110
ILE A  66
 None
 0.99A 4nkxC-3noqA:
undetectable		 4nkxC-3noqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 LEU A 146
ALA A  91
GLY A 111
ALA A 110
ILE A  66
 None
 1.01A 4nkxD-3noqA:
undetectable		 4nkxD-3noqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 ILE A 156
GLY A 155
ASP A  17
LEU A  28
ALA A 163
 None
None
EDO  A 604 ( 4.6A)
None
None
 1.03A 5h5fA-3noqA:
undetectable		 5h5fA-3noqA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		4 / 5 VAL A   3
ASP A  30
PRO A  29
ALA A   2
 None
 1.11A 5otrA-3noqA:
undetectable		 5otrA-3noqA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3noq THIJ/PFPI FAMILY
PROTEIN
(Pseudomonas
fluorescens) 		4 / 7 THR A  19
LEU A  16
ILE A 156
THR A 153
 None
 1.01A 5zsfA-3noqA:
undetectable
5zsfB-3noqA:
undetectable		 5zsfA-3noqA:
16.59
5zsfB-3noqA:
16.59