SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3now'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 GLY A 667
PHE A 710
VAL A 675
LEU A 678
ALA A 698
 None
 1.33A 1e3vA-3nowA:
undetectable		 1e3vA-3nowA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		3 / 3 MET A 889
LEU A 892
SER A 893
 None
 0.50A 1ee2A-3nowA:
undetectable		 1ee2A-3nowA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 MET A 351
LEU A 335
VAL A 307
GLY A 306
 None
 0.89A 1hrkA-3nowA:
undetectable		 1hrkA-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 MET A 351
LEU A 335
VAL A 307
GLY A 306
 None
 0.94A 1hrkB-3nowA:
undetectable		 1hrkB-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 LEU A 722
PRO A 721
LEU A 725
ARG A 699
 None
 1.26A 1hrkB-3nowA:
undetectable		 1hrkB-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 7 SER A 573
ASN A 571
ASP A 531
LYS A 530
 None
 1.34A 1hwiC-3nowA:
0.9		 1hwiC-3nowA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 7 SER A 573
ASN A 571
ASP A 531
LYS A 530
 None
 1.34A 1hwiD-3nowA:
undetectable		 1hwiD-3nowA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 11 LEU A 472
SER A 455
VAL A 423
LEU A 433
LEU A 429
 None
 1.04A 1mx1B-3nowA:
undetectable		 1mx1B-3nowA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
SER A 455
VAL A 423
LEU A 433
LEU A 429
 None
 1.02A 1mx1C-3nowA:
undetectable		 1mx1C-3nowA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
SER A 455
VAL A 423
LEU A 433
LEU A 429
 None
 1.09A 1mx1E-3nowA:
undetectable		 1mx1E-3nowA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 625
ILE A 652
LEU A 656
VAL A 659
ILE A 633
 None
 1.05A 1oipA-3nowA:
undetectable		 1oipA-3nowA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		6 / 12 LEU A 523
VAL A 485
ASP A 538
GLY A 539
ALA A 541
THR A 544
 None
 1.27A 1r9oA-3nowA:
undetectable		 1r9oA-3nowA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 637
CYH A 638
LEU A 640
ALA A 641
MET A 681
 None
 1.00A 1s9pC-3nowA:
undetectable		 1s9pC-3nowA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 6 ALA A 653
LEU A 651
SER A 648
SER A 645
 None
 1.05A 1tz8C-3nowA:
undetectable
1tz8D-3nowA:
undetectable		 1tz8C-3nowA:
9.31
1tz8D-3nowA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 SER A 648
ILE A 652
VAL A 578
THR A 544
 None
 1.25A 1u70A-3nowA:
undetectable		 1u70A-3nowA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		6 / 12 LEU A 847
LEU A 850
LEU A 853
LEU A 826
LEU A 841
THR A 886
 None
 1.44A 1zucB-3nowA:
undetectable		 1zucB-3nowA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 853
LEU A 850
LEU A 847
LEU A 841
LEU A 826
 None
 1.18A 1zucB-3nowA:
undetectable		 1zucB-3nowA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 7 LEU A 172
LEU A 169
ILE A 203
ARG A 162
 None
 1.19A 2hc4A-3nowA:
undetectable		 2hc4A-3nowA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 LEU A 722
PRO A 721
LEU A 725
ARG A 699
 None
 1.25A 2hrcA-3nowA:
undetectable		 2hrcA-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 LEU A 722
PRO A 721
LEU A 725
ARG A 699
 None
 1.20A 2hrcB-3nowA:
undetectable		 2hrcB-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 LEU A 722
PRO A 721
LEU A 725
ARG A 699
 None
 1.27A 2pnjB-3nowA:
undetectable		 2pnjB-3nowA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 7 TRP A 322
CYH A 276
GLN A 254
ILE A 283
 None
 1.00A 2xz5A-3nowA:
undetectable
2xz5B-3nowA:
undetectable		 2xz5A-3nowA:
13.27
2xz5B-3nowA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 7 GLN A 254
ILE A 283
TRP A 322
CYH A 276
 None
 1.02A 2xz5D-3nowA:
undetectable
2xz5E-3nowA:
undetectable		 2xz5D-3nowA:
13.27
2xz5E-3nowA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 828
GLY A 865
LEU A 826
ALA A 906
VAL A 861
 None
 1.08A 2yvlA-3nowA:
undetectable		 2yvlA-3nowA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 828
GLY A 865
LEU A 826
ALA A 906
VAL A 861
 None
 1.10A 2yvlB-3nowA:
undetectable		 2yvlB-3nowA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 LEU A 575
GLN A 649
THR A 643
THR A 580
 None
 1.04A 2zj0D-3nowA:
undetectable		 2zj0D-3nowA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 742
GLY A 712
ILE A 700
LEU A 697
LEU A 722
 None
 0.98A 3adxB-3nowA:
undetectable		 3adxB-3nowA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 LEU A 575
GLN A 649
THR A 643
THR A 580
 None
 1.05A 3ce6B-3nowA:
undetectable		 3ce6B-3nowA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 853
LEU A 850
LEU A 847
LEU A 841
LEU A 826
 None
 1.26A 3d90B-3nowA:
undetectable		 3d90B-3nowA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 787
LEU A 784
GLN A 782
ALA A 780
LEU A 726
 None
 1.18A 3gwuA-3nowA:
undetectable		 3gwuA-3nowA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		3 / 3 ASN A 571
ASP A 531
ARG A 403
 None
 0.90A 3k13A-3nowA:
undetectable		 3k13A-3nowA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
GLY A 495
GLY A 490
LEU A 488
ALA A 511
 None
 0.82A 3ou6A-3nowA:
undetectable		 3ou6A-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
GLY A 495
GLY A 490
LEU A 488
ALA A 511
 None
 0.83A 3ou6B-3nowA:
undetectable		 3ou6B-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
GLY A 495
GLY A 490
LEU A 488
ALA A 512
 None
 1.13A 3ou6B-3nowA:
undetectable		 3ou6B-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
GLY A 495
GLY A 490
LEU A 488
ALA A 511
 None
 0.85A 3ou7B-3nowA:
undetectable		 3ou7B-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 472
GLY A 495
GLY A 490
LEU A 488
ALA A 512
 None
 1.13A 3ou7B-3nowA:
undetectable		 3ou7B-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 LEU A 585
TYR A 542
ALA A 537
GLY A 539
LEU A 563
 None
 1.18A 3ou7D-3nowA:
undetectable		 3ou7D-3nowA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 6 VAL A 291
VAL A 315
ILE A 308
ARG A 330
 None
 1.01A 3pyyA-3nowA:
undetectable		 3pyyA-3nowA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		3 / 3 SER A 455
ASP A 538
ASP A 531
 None
 0.82A 3uj7A-3nowA:
undetectable		 3uj7A-3nowA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA608_0
(SERUM ALBUMIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 PRO A 899
ASP A 900
LEU A 898
ARG A 907
 None
 1.39A 4luhA-3nowA:
0.4		 4luhA-3nowA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 524
ARG A 533
LEU A 523
LEU A 585
LEU A 553
 None
 0.96A 4qynB-3nowA:
undetectable		 4qynB-3nowA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ASP A 344
THR A 405
THR A 409
ALA A 407
ALA A 410
 None
 1.45A 4u15A-3nowA:
undetectable		 4u15A-3nowA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 6 LEU A 310
LEU A 290
SER A 293
VAL A 237
 None
 1.04A 5a6iA-3nowA:
undetectable		 5a6iA-3nowA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.91A 5axaA-3nowA:
undetectable		 5axaA-3nowA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.94A 5axaC-3nowA:
undetectable		 5axaC-3nowA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8A-3nowA:
undetectable		 5hm8A-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8B-3nowA:
undetectable		 5hm8B-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8C-3nowA:
undetectable		 5hm8C-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8D-3nowA:
undetectable		 5hm8D-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8E-3nowA:
undetectable		 5hm8E-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8F-3nowA:
undetectable		 5hm8F-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8G-3nowA:
undetectable		 5hm8G-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 1.00A 5hm8H-3nowA:
undetectable		 5hm8H-3nowA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 ALA A 536
GLY A 490
CYH A 492
LYS A 493
 None
 1.48A 5jliA-3nowA:
undetectable		 5jliA-3nowA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 5 ALA A 536
GLY A 490
CYH A 492
LYS A 493
 None
 1.50A 5jt4A-3nowA:
undetectable		 5jt4A-3nowA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		6 / 10 GLY A 577
VAL A 578
ILE A 633
LEU A 585
VAL A 655
LEU A 637
 None
 1.25A 5lw1E-3nowA:
undetectable		 5lw1E-3nowA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 385
LEU A 336
VAL A 418
GLY A 419
GLY A 414
 None
 0.87A 5nnaA-3nowA:
undetectable		 5nnaA-3nowA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 385
LEU A 336
VAL A 418
GLY A 419
GLY A 414
 None
 0.89A 5nnaB-3nowA:
undetectable		 5nnaB-3nowA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 385
LEU A 336
VAL A 418
GLY A 419
GLY A 414
 None
 0.87A 5nnaC-3nowA:
undetectable		 5nnaC-3nowA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 385
LEU A 336
VAL A 418
GLY A 419
GLY A 414
 None
 0.86A 5nnaD-3nowA:
undetectable		 5nnaD-3nowA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 12 ILE A 256
LEU A 214
LEU A 286
LEU A 310
LEU A 290
 None
 1.17A 5tiwA-3nowA:
undetectable		 5tiwA-3nowA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 LYS A 905
ALA A 906
VAL A 909
GLY A 865
 None
 1.00A 5v0vA-3nowA:
undetectable		 5v0vA-3nowA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.91A 5v96A-3nowA:
undetectable		 5v96A-3nowA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.92A 5v96B-3nowA:
undetectable		 5v96B-3nowA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.90A 5v96C-3nowA:
undetectable		 5v96C-3nowA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 4 GLU A 198
THR A 195
THR A 248
LEU A 169
 None
 0.91A 5v96D-3nowA:
undetectable		 5v96D-3nowA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 ARG A 313
ARG A 680
ASN A 371
TYR A 317
 None
 1.22A 6hisA-3nowA:
2.1
6hisB-3nowA:
2.1		 6hisA-3nowA:
7.17
6hisB-3nowA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 ARG A 313
ARG A 680
ASN A 371
TYR A 317
 None
 1.22A 6hisB-3nowA:
2.1
6hisC-3nowA:
2.1		 6hisB-3nowA:
7.17
6hisC-3nowA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 ARG A 313
ARG A 680
ASN A 371
TYR A 317
 None
 1.22A 6hisC-3nowA:
2.1
6hisD-3nowA:
2.2		 6hisC-3nowA:
7.17
6hisD-3nowA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 ARG A 313
ARG A 680
ASN A 371
TYR A 317
 None
 1.20A 6hisD-3nowA:
2.2
6hisE-3nowA:
2.1		 6hisD-3nowA:
7.17
6hisE-3nowA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		4 / 8 ASN A 371
TYR A 317
ARG A 313
ARG A 680
 None
 1.22A 6hisA-3nowA:
2.1
6hisE-3nowA:
2.1		 6hisA-3nowA:
7.17
6hisE-3nowA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3now UNC-45 PROTEIN,
SD10334P
(Drosophila
melanogaster) 		5 / 9 ILE A 311
ILE A 308
GLU A 328
VAL A 291
ILE A 294
 None
 1.27A 6hloA-3nowA:
undetectable		 6hloA-3nowA:
22.00