SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 3nps S4 FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 7 LEU C 135
THR C 172
SER C 162
THR C 164
 None
 0.71A 1ictD-3npsC:
undetectable		 1ictD-3npsC:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3nps S4 FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL C 150
TYR C 192
LYS C 188
GLU C 187
 None
 1.07A 3hs4A-3npsC:
undetectable		 3hs4A-3npsC:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 3nps S4 FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 7 THR C  76
ALA C  74
SER C  22
THR C  20
 None
 0.74A 4pwjB-3npsC:
undetectable		 4pwjB-3npsC:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 3nps S4 FAB LIGHT CHAIN
(Homo
sapiens) 		5 / 7 TYR C  32
SER C  34
TYR C  36
TYR C  49
PRO C  55
 None
 0.70A 5aclA-3npsC:
21.5		 5aclA-3npsC:
65.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3nps S4 FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLY C  68
THR C  69
SER C  70
GLY C  25
 None
 0.90A 5k4pA-3npsC:
undetectable		 5k4pA-3npsC:
19.01