SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 261
THR A 258
ASN A 260
ASN A 231
 None
 1.00A 1dssG-3nqhA:
undetectable		 1dssG-3nqhA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 261
THR A 258
ASN A 260
ASN A 231
 None
 1.01A 1dssR-3nqhA:
undetectable		 1dssR-3nqhA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 266
PRO A 277
SER A 308
VAL A 302
PHE A 212
 None
 1.40A 1fdwA-3nqhA:
undetectable		 1fdwA-3nqhA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  97
LEU A 152
LEU A 153
LEU A 148
PHE A  72
 None
 1.24A 1fmlB-3nqhA:
undetectable		 1fmlB-3nqhA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 SER A 204
GLY A 180
PHE A 220
GLY A 206
PHE A 236
 None
 1.44A 1ho5A-3nqhA:
undetectable		 1ho5A-3nqhA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 204
GLY A 180
PHE A 220
GLY A 206
PHE A 236
 None
 1.35A 1ho5B-3nqhA:
undetectable		 1ho5B-3nqhA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 404
PRO A 287
THR A 226
ARG A 443
 None
 1.26A 1i2wA-3nqhA:
undetectable		 1i2wA-3nqhA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A 402
SER A 285
ASN A 260
SER A 447
 None
 1.24A 1kiaB-3nqhA:
undetectable		 1kiaB-3nqhA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 402
SER A 285
ASN A 260
SER A 447
 None
 1.23A 1kiaC-3nqhA:
undetectable		 1kiaC-3nqhA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 284
GLY A 281
THR A 264
SER A 223
 None
 1.09A 2o5yH-3nqhA:
undetectable
2o5yL-3nqhA:
undetectable		 2o5yH-3nqhA:
21.44
2o5yL-3nqhA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 SER A 187
VAL A 119
TYR A 121
ASP A 189
 None
 1.16A 2x45A-3nqhA:
undetectable		 2x45A-3nqhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 187
VAL A 119
TYR A 121
ASP A 189
 None
 1.17A 2x45B-3nqhA:
undetectable		 2x45B-3nqhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 187
VAL A 119
TYR A 121
ASP A 189
 None
 1.16A 2x45C-3nqhA:
undetectable		 2x45C-3nqhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 223
GLU A 105
ASP A 126
 None
GOL  A 501 (-2.8A)
None
 0.62A 2zulA-3nqhA:
undetectable		 2zulA-3nqhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 187
VAL A 119
TYR A 121
ASP A 189
 None
 1.15A 3bu1A-3nqhA:
undetectable		 3bu1A-3nqhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 223
GLU A 105
ASP A 126
 None
GOL  A 501 (-2.8A)
None
 0.60A 3dmhA-3nqhA:
undetectable		 3dmhA-3nqhA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 261
THR A 258
ASN A 260
ASN A 231
 None
 0.98A 3dmtC-3nqhA:
undetectable		 3dmtC-3nqhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 368
PHE A 366
SER A 399
MET A 386
LEU A 426
 None
 1.47A 4a83A-3nqhA:
undetectable		 4a83A-3nqhA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A  33
ASN A  42
TYR A  75
LEU A  57
 None
 1.44A 4f8yA-3nqhA:
undetectable
4f8yB-3nqhA:
undetectable		 4f8yA-3nqhA:
18.65
4f8yB-3nqhA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 180
GLY A 181
PHE A 220
GLY A 206
PHE A 236
 None
 1.29A 4h2fA-3nqhA:
undetectable		 4h2fA-3nqhA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ALA A 384
ASP A 456
ILE A 454
ILE A 338
 None
 0.89A 4kttB-3nqhA:
undetectable		 4kttB-3nqhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 402
TRP A 346
SER A 447
 None
 1.07A 4lrhA-3nqhA:
undetectable		 4lrhA-3nqhA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 ILE A 428
GLY A 382
PHE A 403
SER A 355
VAL A 401
 None
 1.25A 5i6xA-3nqhA:
undetectable		 5i6xA-3nqhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A  44
ILE A  40
VAL A  41
TYR A 295
 None
 1.18A 5kkzC-3nqhA:
0.7
5kkzE-3nqhA:
undetectable		 5kkzC-3nqhA:
14.22
5kkzE-3nqhA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  40
VAL A  41
TYR A 295
HIS A  44
 None
 1.20A 5kkzK-3nqhA:
undetectable
5kkzQ-3nqhA:
0.8		 5kkzK-3nqhA:
21.17
5kkzQ-3nqhA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A  44
ILE A  40
VAL A  41
TYR A 295
 None
 1.04A 5kkzM-3nqhA:
undetectable
5kkzO-3nqhA:
undetectable		 5kkzM-3nqhA:
14.22
5kkzO-3nqhA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 414
SER A 399
VAL A 401
PRO A 417
ALA A 292
 None
 1.35A 5tzoA-3nqhA:
undetectable		 5tzoA-3nqhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLY A 368
LEU A 419
ILE A 388
LEU A 426
ILE A  31
 None
 0.89A 5vkqC-3nqhA:
undetectable
5vkqD-3nqhA:
undetectable		 5vkqC-3nqhA:
13.46
5vkqD-3nqhA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  60
TRP A 228
HIS A 123
 None
 1.06A 5xipA-3nqhA:
undetectable		 5xipA-3nqhA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3nqh GLYCOSYL HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ALA A 407
ARG A 413
ASP A 402
ILE A  31
THR A 294
 None
 1.31A 5y80A-3nqhA:
undetectable		 5y80A-3nqhA:
10.88