SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 SER A 133
VAL A  36
PHE A 212
VAL A 135
ALA A  34
 None
None
PEG  A 329 (-4.8A)
None
None
 1.17A 1q23H-3nqiA:
undetectable
1q23I-3nqiA:
undetectable		 1q23H-3nqiA:
18.15
1q23I-3nqiA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 10 PHE A 128
SER A 133
VAL A  36
PHE A 212
VAL A 135
 PEG  A 329 ( 4.8A)
None
None
PEG  A 329 (-4.8A)
None
 1.40A 1q23K-3nqiA:
undetectable		 1q23K-3nqiA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 7 LEU A 191
THR A 172
GLY A 115
ASP A 116
 None
 1.05A 2ddwB-3nqiA:
undetectable		 2ddwB-3nqiA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
PHE A 212
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-4.8A)
None
None
None
 1.34A 3s8pA-3nqiA:
undetectable		 3s8pA-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.45A 3s8pA-3nqiA:
undetectable		 3s8pA-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
PHE A 212
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-4.8A)
None
None
None
 1.35A 3s8pB-3nqiA:
undetectable		 3s8pB-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.45A 3s8pB-3nqiA:
undetectable		 3s8pB-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.46A 4bupA-3nqiA:
undetectable		 4bupA-3nqiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
PHE A 212
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-4.8A)
None
None
None
 1.34A 4bupB-3nqiA:
undetectable		 4bupB-3nqiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.46A 4bupB-3nqiA:
undetectable		 4bupB-3nqiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
PHE A 212
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-4.8A)
None
None
None
 1.26A 5cprB-3nqiA:
undetectable		 5cprB-3nqiA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 118
THR A 119
SER A 114
GLY A 115
THR A 108
 None
 0.99A 5l5zV-3nqiA:
undetectable
5l5zb-3nqiA:
undetectable		 5l5zV-3nqiA:
24.46
5l5zb-3nqiA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 118
THR A 119
SER A 114
GLY A 115
THR A 108
 None
 1.00A 5lf3b-3nqiA:
undetectable		 5lf3b-3nqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 118
THR A 119
SER A 114
GLY A 115
THR A 108
 None
 1.01A 5lf3N-3nqiA:
undetectable		 5lf3N-3nqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 118
THR A 119
SER A 114
GLY A 115
THR A 108
 None
 0.98A 5lf7V-3nqiA:
undetectable
5lf7b-3nqiA:
undetectable		 5lf7V-3nqiA:
23.81
5lf7b-3nqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 118
THR A 119
SER A 114
GLY A 115
THR A 108
 None
 0.96A 5lf7H-3nqiA:
undetectable
5lf7N-3nqiA:
undetectable		 5lf7H-3nqiA:
23.81
5lf7N-3nqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.37A 5wbvA-3nqiA:
undetectable		 5wbvA-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 100
SER A 210
HIS A 169
TYR A 151
PHE A 171
 None
PEG  A 329 (-3.6A)
None
None
None
 1.39A 5wbvB-3nqiA:
undetectable		 5wbvB-3nqiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3nqi PUTATIVE LIPOPROTEIN
(Bacteroides
fragilis) 		4 / 5 THR A 144
ARG A  69
THR A 107
ASP A 116
 None
 1.15A 6ecxA-3nqiA:
undetectable		 6ecxA-3nqiA:
19.87