SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ALA A  37
TYR A  61
ILE A  39
ILE A  49
 None
 1.04A 2dcfA-3nqkA:
undetectable		 2dcfA-3nqkA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A 295
PHE A 293
ALA A 186
THR A 206
LEU A 225
 None
 1.19A 2wuzA-3nqkA:
undetectable		 2wuzA-3nqkA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A 295
PHE A 293
ALA A 186
THR A 206
LEU A 225
 None
 1.19A 2wuzB-3nqkA:
undetectable		 2wuzB-3nqkA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 ALA A  37
TYR A  61
ILE A  39
ILE A  49
 None
 1.05A 2zm7A-3nqkA:
undetectable		 2zm7A-3nqkA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 8 ALA A  37
TYR A  61
ILE A  39
ILE A  49
TYR A  50
 None
 1.32A 2zmaA-3nqkA:
undetectable		 2zmaA-3nqkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 VAL A 127
LEU A 172
ILE A  39
LEU A 129
 None
 0.97A 3kk6A-3nqkA:
undetectable		 3kk6A-3nqkA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 8 PHE A 293
TYR A 295
ALA A 186
THR A 206
LEU A 225
 None
 1.50A 3l4dA-3nqkA:
undetectable		 3l4dA-3nqkA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_C_TPFC490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 9 PHE A 293
TYR A 295
ALA A 186
THR A 206
LEU A 225
 None
 1.48A 3l4dC-3nqkA:
undetectable		 3l4dC-3nqkA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_B_ASDB126_1
(STEROID
DELTA-ISOMERASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A 184
ASN A 178
LEU A 250
PHE A 221
VAL A 242
 None
 1.46A 3nuvB-3nqkA:
1.6		 3nuvB-3nqkA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 PHE A  35
THR A 118
PHE A 115
ILE A  65
 None
None
EDO  A 402 (-3.9A)
None
 1.02A 4jx1E-3nqkA:
undetectable		 4jx1E-3nqkA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 3nqk UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 ILE A 219
ASN A 179
SER A 273
SER A 272
LEU A 250
 None
 1.42A 6chgC-3nqkA:
undetectable		 6chgC-3nqkA:
21.68