SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y05_A_RALA802_1 (PROSTAGLANDIN REDUCTASE 1)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 7	VAL A 142 GLY A 49 VAL A 92 ASP A 41	None	0.93A	2y05A-3nqnA: undetectable 2y05B-3nqnA: undetectable	2y05A-3nqnA: 20.91 2y05B-3nqnA: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3008_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 7	HIS A 113 VAL A 90 GLN A 111 ALA A 5	None	1.06A	3kp6B-3nqnA: undetectable	3kp6B-3nqnA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_B_9PLB1_1 (CYTOCHROME P450 2A13)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 6	PHE A 108 PHE A 106 ALA A 105 THR A 97	MRD A 161 ( 4.7A) None MRD A 163 (-3.8A) MRD A 163 ( 3.7A)	1.11A	3t3sB-3nqnA: undetectable	3t3sB-3nqnA: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_A_9PLA501_1 (CYTOCHROME P450 2E1)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 6	PHE A 108 LEU A 37 ALA A 30 LEU A 78	MRD A 161 ( 4.7A) None MRD A 161 (-3.2A) MRD A 161 ( 4.5A)	0.92A	3t3zA-3nqnA: undetectable	3t3zA-3nqnA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_B_9PLB501_1 (CYTOCHROME P450 2E1)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 6	PHE A 108 LEU A 37 ALA A 30 LEU A 78	MRD A 161 ( 4.7A) None MRD A 161 (-3.2A) MRD A 161 ( 4.5A)	0.94A	3t3zB-3nqnA: undetectable	3t3zB-3nqnA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_D_9PLD501_1 (CYTOCHROME P450 2E1)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	4 / 6	PHE A 108 LEU A 37 ALA A 30 LEU A 78	MRD A 161 ( 4.7A) None MRD A 161 (-3.2A) MRD A 161 ( 4.5A)	0.94A	3t3zD-3nqnA: undetectable	3t3zD-3nqnA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_B_ADNB301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	5 / 10	ALA A 134 ARG A 137 GLY A 136 LEU A 114 LEU A 139	None	1.09A	3wdmB-3nqnA: undetectable	3wdmB-3nqnA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_D_ADND301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	3nqn	UNCHARACTERIZED PROTEIN (Deinococcus radiodurans)	5 / 10	ALA A 134 ARG A 137 GLY A 136 LEU A 114 LEU A 139	None	1.15A	3wdmD-3nqnA: undetectable	3wdmD-3nqnA: 21.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y05_A_RALA802_1","PROSTAGLANDIN REDUCTASE 1;PROSTAGLANDIN REDUCTASE 1","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"VAL A 142;GLY A  49;VAL A  92;ASP A  41","None","0.93A","2y05A-3nqnA:undetectable;2y05B-3nqnA:undetectable","2y05A-3nqnA:20.91;2y05B-3nqnA:20.91"],["3KP6_B_SALB3008_1","TRANSCRIPTIONAL REGULATOR TCAR","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"HIS A 113;VAL A  90;GLN A 111;ALA A   5","None","1.06A","3kp6B-3nqnA:undetectable","3kp6B-3nqnA:19.88"],["3T3S_B_9PLB1_1","CYTOCHROME P450 2A13","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"PHE A 108;PHE A 106;ALA A 105;THR A  97","MRD A 161 ( 4.7A);None;MRD A 163 (-3.8A);MRD A 163 ( 3.7A)","1.11A","3t3sB-3nqnA:undetectable","3t3sB-3nqnA:15.91"],["3T3Z_A_9PLA501_1","CYTOCHROME P450 2E1","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"PHE A 108;LEU A  37;ALA A  30;LEU A  78","MRD A 161 ( 4.7A);None;MRD A 161 (-3.2A);MRD A 161 ( 4.5A)","0.92A","3t3zA-3nqnA:undetectable","3t3zA-3nqnA:16.09"],["3T3Z_B_9PLB501_1","CYTOCHROME P450 2E1","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"PHE A 108;LEU A  37;ALA A  30;LEU A  78","MRD A 161 ( 4.7A);None;MRD A 161 (-3.2A);MRD A 161 ( 4.5A)","0.94A","3t3zB-3nqnA:undetectable","3t3zB-3nqnA:16.09"],["3T3Z_D_9PLD501_1","CYTOCHROME P450 2E1","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",4,"PHE A 108;LEU A  37;ALA A  30;LEU A  78","MRD A 161 ( 4.7A);None;MRD A 161 (-3.2A);MRD A 161 ( 4.5A)","0.94A","3t3zD-3nqnA:undetectable","3t3zD-3nqnA:16.09"],["3WDM_B_ADNB301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",5,"ALA A 134;ARG A 137;GLY A 136;LEU A 114;LEU A 139","None","1.09A","3wdmB-3nqnA:undetectable","3wdmB-3nqnA:21.07"],["3WDM_D_ADND301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","3nqn","UNCHARACTERIZED PROTEIN","Deinococcus radiodurans",5,"ALA A 134;ARG A 137;GLY A 136;LEU A 114;LEU A 139","None","1.15A","3wdmD-3nqnA:undetectable","3wdmD-3nqnA:21.07"]]