SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nrf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nrf APAG PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 106
ALA A  31
LEU A 118
ALA A  72
 None
 1.17A 2vcvA-3nrfA:
undetectable		 2vcvA-3nrfA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3nrf APAG PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 PHE A  30
LEU A  82
ASP A 103
GLY A 102
ALA A  50
 MRD  A 128 (-4.4A)
None
None
None
None
 1.09A 5fctA-3nrfA:
undetectable		 5fctA-3nrfA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3nrf APAG PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 PHE A  30
LEU A  82
ASP A 103
GLY A 102
ALA A  50
 MRD  A 128 (-4.4A)
None
None
None
None
 1.20A 6r2eF-3nrfA:
undetectable		 6r2eF-3nrfA:
14.86