SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nrg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 3nrg TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Chloroflexus
aurantiacus) 		4 / 5 LEU A  22
ASP A  19
TYR A  62
LEU A  63
 CL  A 218 ( 4.7A)
None
None
None
 1.22A 4wozF-3nrgA:
undetectable
4wozH-3nrgA:
undetectable		 4wozF-3nrgA:
24.00
4wozH-3nrgA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 3nrg TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Chloroflexus
aurantiacus) 		4 / 6 LEU A 140
LEU A 150
ILE A 206
PHE A  87
 None
 1.20A 4y4dA-3nrgA:
undetectable		 4y4dA-3nrgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3nrg TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Chloroflexus
aurantiacus) 		3 / 3 ASN A 181
ALA A 183
ARG A 187
 None
 0.77A 5cvtB-3nrgA:
undetectable		 5cvtB-3nrgA:
22.90