SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nrh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ILE A 123
LEU A  79
PHE A  23
LEU A  46
ILE A 119
 None
 1.10A 1cd2A-3nrhA:
undetectable		 1cd2A-3nrhA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		4 / 8 ARG A  35
GLU A  89
SER A 113
LEU A  83
 None
 0.92A 2bxgA-3nrhA:
undetectable		 2bxgA-3nrhA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ALA A  20
TRP A 153
LEU A  49
LEU A  48
LEU A  56
 None
 0.99A 2qxsA-3nrhA:
undetectable		 2qxsA-3nrhA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		4 / 6 PHE A  38
ASP A  91
LEU A  83
THR A 160
 None
 1.36A 4paeA-3nrhA:
undetectable		 4paeA-3nrhA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 LEU A  87
VAL A 167
THR A 160
PHE A  23
GLY A 154
 None
 1.16A 4q15A-3nrhA:
undetectable		 4q15A-3nrhA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 LEU A  87
VAL A 167
THR A 160
PHE A  23
GLY A 154
 None
 1.13A 4q15B-3nrhA:
undetectable		 4q15B-3nrhA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 9 ILE A 112
PHE A  38
LEU A 164
LEU A  27
PHE A  23
 None
 1.20A 4qopA-3nrhA:
undetectable		 4qopA-3nrhA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 9 ILE A 112
PHE A  38
LEU A 164
LEU A  27
PHE A  23
 None
 1.19A 4qopB-3nrhA:
undetectable		 4qopB-3nrhA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ALA A  20
TRP A 153
LEU A  49
LEU A  48
LEU A  56
 None
 0.94A 4xi3B-3nrhA:
undetectable		 4xi3B-3nrhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ALA A  20
TRP A 153
LEU A  49
LEU A  48
LEU A  56
 None
 0.88A 4xi3C-3nrhA:
undetectable		 4xi3C-3nrhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ALA A  20
TRP A 153
LEU A  49
LEU A  48
LEU A  56
 None
 0.93A 4xi3D-3nrhA:
undetectable		 4xi3D-3nrhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 11 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.46A 5iqeA-3nrhA:
1.9		 5iqeA-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_B_NMYB600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 10 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.47A 5iqeB-3nrhA:
2.6		 5iqeB-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.46A 5iqeC-3nrhA:
2.7		 5iqeC-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 10 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.49A 5iqgA-3nrhA:
2.6		 5iqgA-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 10 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.49A 5iqgB-3nrhA:
2.6		 5iqgB-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 10 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.50A 5iqgC-3nrhA:
2.0		 5iqgC-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 10 ASP A 118
ASP A 115
TYR A  76
GLU A  77
GLU A  73
 None
 1.49A 5iqgD-3nrhA:
1.9		 5iqgD-3nrhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 LEU A  87
VAL A 167
THR A 160
PHE A  23
GLY A 154
 None
 1.15A 5xipA-3nrhA:
undetectable		 5xipA-3nrhA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3nrh UNCHARACTERIZED
PROTEIN BF1032
(Bacteroides
fragilis) 		5 / 12 LEU A  87
VAL A 167
THR A 160
PHE A  23
GLY A 154
 None
 1.13A 5xipC-3nrhA:
undetectable		 5xipC-3nrhA:
15.73