SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nro'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ARG A 222
ASP A 219
ILE A 226
ASN A 230
 None
 1.10A 2jc9A-3nroA:
undetectable		 2jc9A-3nroA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A 130
GLY A 125
ASP A 305
ASP A 114
 None
 1.14A 2oxtB-3nroA:
undetectable		 2oxtB-3nroA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 228
LEU A 166
ILE A 158
THR A 254
LEU A  77
 None
 1.18A 3a50E-3nroA:
undetectable		 3a50E-3nroA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		5 / 10 PHE A 163
ASN A 251
ASP A 168
VAL A 167
LEU A 201
 None
 1.36A 3ay0A-3nroA:
undetectable		 3ay0A-3nroA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		5 / 10 VAL A 248
GLY A 249
VAL A 167
ASN A 251
GLY A 162
 None
 1.32A 3km6A-3nroA:
undetectable		 3km6A-3nroA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		5 / 9 VAL A 248
GLY A 249
VAL A 167
ASN A 251
GLY A 162
 None
 1.31A 3kmoA-3nroA:
undetectable		 3kmoA-3nroA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		3 / 3 SER A  80
ALA A  91
THR A 139
 None
 0.69A 5n0xB-3nroA:
undetectable		 5n0xB-3nroA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3nro LMO1026 PROTEIN
(Listeria
monocytogenes) 		3 / 3 LEU A 195
ASP A 165
ILE A 158
 None
 0.63A 6dh0B-3nroA:
undetectable		 6dh0B-3nroA:
16.54