SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ntk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.16A 2eimJ-3ntkA:
undetectable		 2eimJ-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.14A 2eimW-3ntkA:
undetectable		 2eimW-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		5 / 12 LEU A2398
ALA A2397
CYH A2423
THR A2436
PHE A2439
 None
 1.22A 2oaxB-3ntkA:
undetectable		 2oaxB-3ntkA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		5 / 12 LEU A2398
ALA A2397
CYH A2423
THR A2436
PHE A2439
 None
 1.26A 2oaxF-3ntkA:
undetectable		 2oaxF-3ntkA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.21A 3ag1J-3ntkA:
undetectable		 3ag1J-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.21A 3ag4J-3ntkA:
undetectable		 3ag4J-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.17A 5w97J-3ntkA:
undetectable		 5w97J-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.20A 5wauJ-3ntkA:
undetectable		 5wauJ-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.21A 5x19J-3ntkA:
undetectable		 5x19J-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.22A 5x1bJ-3ntkA:
undetectable		 5x1bJ-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.16A 5x1bW-3ntkA:
undetectable		 5x1bW-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.20A 5x1fW-3ntkA:
undetectable		 5x1fW-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.20A 5z86J-3ntkA:
undetectable		 5z86J-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 6 ALA A2450
GLY A2494
THR A2490
ILE A2487
 None
 0.89A 6f8cA-3ntkA:
undetectable		 6f8cA-3ntkA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.19A 6nknJ-3ntkA:
undetectable		 6nknJ-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ntk MATERNAL PROTEIN
TUDOR
(Drosophila
melanogaster) 		4 / 5 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.22A 6nknW-3ntkA:
undetectable		 6nknW-3ntkA:
16.88