SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ntn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3ntn USPA1
(Moraxella
catarrhalis) 		4 / 7 ASN A 216
ALA A 222
ALA A 208
GLN A 200
 None
 0.87A 3a2qA-3ntnA:
undetectable		 3a2qA-3ntnA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 224
ASN A 227
ILE A 237
GLY A 270
SER A 255
 None
 0.99A 3hs6B-3ntnA:
undetectable		 3hs6B-3ntnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 203
GLY A 188
ASN A 213
LEU A 223
GLY A 210
 None
 1.07A 4fp9A-3ntnA:
undetectable		 4fp9A-3ntnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 203
GLY A 188
ASN A 213
LEU A 223
GLY A 210
 None
 1.07A 4fp9C-3ntnA:
undetectable		 4fp9C-3ntnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 203
GLY A 188
ASN A 213
LEU A 223
GLY A 210
 None
 1.05A 4fp9D-3ntnA:
undetectable		 4fp9D-3ntnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 203
GLY A 188
ASN A 213
LEU A 223
GLY A 210
 None
 1.06A 4fp9F-3ntnA:
undetectable		 4fp9F-3ntnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ntn USPA1
(Moraxella
catarrhalis) 		5 / 9 ALA A 208
ALA A 201
SER A 206
ALA A 186
ALA A 194
 None
 1.24A 4twdA-3ntnA:
undetectable
4twdB-3ntnA:
undetectable
4twdC-3ntnA:
undetectable
4twdD-3ntnA:
undetectable
4twdE-3ntnA:
undetectable		 4twdA-3ntnA:
20.07
4twdB-3ntnA:
20.07
4twdC-3ntnA:
20.07
4twdD-3ntnA:
20.07
4twdE-3ntnA:
20.07