SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ntt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 SER A 501
THR A 472
GLN A 507
 None
 0.83A 2fk8A-3nttA:
undetectable		 2fk8A-3nttA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 GLN A 507
THR A 491
TRP A 475
 None
 1.08A 2rctA-3nttA:
undetectable		 2rctA-3nttA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 4 PHE A 489
TYR A 502
ILE A 528
LEU A 523
 None
 0.99A 3sudA-3nttA:
undetectable		 3sudA-3nttA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 PRO A 269
THR A 268
LEU A 637
 None
 0.65A 3ttrA-3nttA:
undetectable		 3ttrA-3nttA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 6 THR A 349
CYH A 352
GLY A 351
ASP A 274
 None
 1.25A 3w9tE-3nttA:
undetectable		 3w9tE-3nttA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 6 LEU A 341
TYR A 343
LEU A 637
TYR A 366
 None
 1.21A 4f3tA-3nttA:
undetectable		 4f3tA-3nttA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 GLY A 510
GLU A 552
THR A 512
 None
 0.56A 4kouA-3nttA:
undetectable		 4kouA-3nttA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 6 TYR A 247
ASN A 243
GLU A 389
TYR A 368
 None
NA  A 726 (-4.6A)
None
None
 1.37A 4twdG-3nttA:
undetectable
4twdH-3nttA:
0.9		 4twdG-3nttA:
17.68
4twdH-3nttA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.47A 4v2yA-3nttA:
undetectable		 4v2yA-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.47A 4v2yB-3nttA:
undetectable		 4v2yB-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.50A 4v2zA-3nttA:
undetectable		 4v2zA-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 8 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.43A 4v2zB-3nttA:
undetectable		 4v2zB-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.48A 4v30A-3nttA:
undetectable		 4v30A-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 8 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.36A 4v30B-3nttA:
undetectable		 4v30B-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 6 LEU A 341
TYR A 343
PRO A 342
TYR A 366
 None
 1.32A 4z4gA-3nttA:
undetectable		 4z4gA-3nttA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.48A 5amiA-3nttA:
undetectable		 5amiA-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.47A 5amjA-3nttA:
undetectable		 5amjA-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.45A 5amjB-3nttA:
undetectable		 5amjB-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.43A 5amkB-3nttA:
undetectable		 5amkB-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.50A 5oh1A-3nttA:
undetectable		 5oh1A-3nttA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.43A 5oh1B-3nttA:
undetectable		 5oh1B-3nttA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.49A 5oh3A-3nttA:
undetectable		 5oh3A-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 PRO A 299
PHE A 627
TRP A 608
TYR A 343
 None
 1.47A 5oh3B-3nttA:
undetectable		 5oh3B-3nttA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3ntt CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		5 / 12 GLY A 605
GLY A 626
ALA A 609
PHE A 408
PHE A 297
 None
 0.96A 6nj9K-3nttA:
undetectable		 6nj9K-3nttA:
18.74