SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ntu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		4 / 6 VAL A 173
MET A 162
ARG A 158
THR A 153
 None
None
ANP  A 401 (-3.5A)
MG  A 501 ( 4.6A)
 1.20A 2x2iA-3ntuA:
undetectable		 2x2iA-3ntuA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		4 / 8 GLU A 151
SER A 215
GLN A 257
VAL A 288
 ANP  A 401 (-4.0A)
None
None
None
 1.05A 3b9lA-3ntuA:
undetectable		 3b9lA-3ntuA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		3 / 3 THR A 283
SER A  99
PHE A 103
 None
MG  A 502 ( 4.1A)
None
 0.79A 3d4sA-3ntuA:
undetectable		 3d4sA-3ntuA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		5 / 9 HIS A 305
LEU A 306
LEU A 300
THR A 101
LEU A  95
 None
 1.45A 3q1eB-3ntuA:
undetectable
3q1eD-3ntuA:
undetectable		 3q1eB-3ntuA:
17.35
3q1eD-3ntuA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_B_SAMB605_0
(GUANINE-N7
METHYLTRANSFERASE)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		5 / 11 PRO A 143
ALA A 145
ASN A 249
CYH A 250
VAL A 252
 None
 1.48A 5c8tB-3ntuA:
1.7		 5c8tB-3ntuA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3ntu DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
voltae) 		4 / 7 HIS A 276
ILE A 277
VAL A 278
ARG A 230
 None
 1.30A 5kkzC-3ntuA:
undetectable
5kkzE-3ntuA:
undetectable		 5kkzC-3ntuA:
22.19
5kkzE-3ntuA:
20.88