SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ntv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLY A  79
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
None
SO4  A 233 (-4.9A)
None
None
 1.18A 1h1dA-3ntvA:
21.5		 1h1dA-3ntvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A 204
LEU A 225
LEU A 208
SER A 228
 None
 1.04A 1i7zA-3ntvA:
undetectable		 1i7zA-3ntvA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 8 GLU A  77
GLY A  79
GLU A 102
ARG A 103
 SO4  A 233 (-4.0A)
None
None
None
 0.72A 1jg4A-3ntvA:
11.5		 1jg4A-3ntvA:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A 159
TYR A 204
LEU A 208
GLY A 213
 None
 0.93A 1rmtC-3ntvA:
4.3		 1rmtC-3ntvA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
None
 1.14A 1vidA-3ntvA:
21.4		 1vidA-3ntvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ASN A 104
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 0.51A 2cl5B-3ntvA:
21.3		 2cl5B-3ntvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLY A  79
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
None
SO4  A 233 (-4.9A)
None
None
 1.23A 2zthA-3ntvA:
14.6		 2zthA-3ntvA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ASN A 104
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 0.49A 2zvjA-3ntvA:
21.4		 2zvjA-3ntvA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
SO4  A 233 (-4.9A)
None
None
 0.94A 3a7eA-3ntvA:
21.5		 3a7eA-3ntvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 6 GLY A  79
SER A  85
ILE A 101
GLU A 102
 None
SO4  A 233 (-2.6A)
None
None
 0.28A 3a7eA-3ntvA:
21.5		 3a7eA-3ntvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLY A  79
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
None
SO4  A 233 (-4.9A)
None
None
 1.17A 3bwmA-3ntvA:
20.9		 3bwmA-3ntvA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 1.14A 3bwyA-3ntvA:
20.9		 3bwyA-3ntvA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLU A  77
GLY A  79
ILE A 101
GLU A 102
ALA A 131
 SO4  A 233 (-4.0A)
None
None
None
None
 0.51A 3dxyA-3ntvA:
12.4		 3dxyA-3ntvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 7 GLY A 181
ASP A 185
ILE A 188
VAL A 198
 None
 0.80A 3fi0E-3ntvA:
2.3		 3fi0E-3ntvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 8 GLY A 181
ASP A 185
ILE A 188
VAL A 198
 None
 0.77A 3fi0G-3ntvA:
undetectable		 3fi0G-3ntvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 8 GLY A 181
ASP A 185
ILE A 188
VAL A 198
 None
 0.78A 3fi0Q-3ntvA:
2.2		 3fi0Q-3ntvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLY A  79
ILE A 101
GLU A 102
ALA A 131
ASP A 149
 None
 0.89A 3nmuB-3ntvA:
undetectable
3nmuJ-3ntvA:
13.5		 3nmuB-3ntvA:
23.08
3nmuJ-3ntvA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S68_A_SAMA228_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 10 GLU A  77
GLY A  79
SER A  85
GLU A 102
GLN A 154
 SO4  A 233 (-4.0A)
None
SO4  A 233 (-2.6A)
None
None
 1.00A 3s68A-3ntvA:
20.6		 3s68A-3ntvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 11 LEU A  60
VAL A  55
SER A  39
GLU A  41
PHE A 120
 None
SO4  A 233 (-4.2A)
None
None
None
 1.43A 3tbgA-3ntvA:
undetectable		 3tbgA-3ntvA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 4 MET A  87
SER A  86
LEU A 115
VAL A 124
 None
 1.35A 3vlnA-3ntvA:
undetectable		 3vlnA-3ntvA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		3 / 3 ASN A 104
GLU A 102
ARG A 103
 None
 1.08A 3wxoA-3ntvA:
undetectable		 3wxoA-3ntvA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 1.15A 4xucA-3ntvA:
20.9		 4xucA-3ntvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ILE A 101
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 0.27A 4xucA-3ntvA:
20.9		 4xucA-3ntvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 1.17A 4xudA-3ntvA:
21.0		 4xudA-3ntvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ILE A 101
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 0.28A 4xudA-3ntvA:
21.0		 4xudA-3ntvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 5 GLY A  79
TYR A  84
SER A  85
GLU A 102
 None
SO4  A 233 (-4.9A)
SO4  A 233 (-2.6A)
None
 0.45A 4xueA-3ntvA:
21.2		 4xueA-3ntvA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 VAL A  55
GLY A  79
TYR A  84
SER A  85
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
None
SO4  A 233 (-4.9A)
SO4  A 233 (-2.6A)
None
None
 1.12A 4xueB-3ntvA:
20.9		 4xueB-3ntvA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ASN A 104
GLN A 154
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
None
 1.07A 5fhrA-3ntvA:
18.9		 5fhrA-3ntvA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ASN A 104
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
 0.48A 5fhrB-3ntvA:
18.8		 5fhrB-3ntvA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		3 / 3 ALA A 111
ASN A 114
LEU A 115
 None
 0.45A 5i1nC-3ntvA:
undetectable		 5i1nC-3ntvA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		3 / 3 ALA A 111
ASN A 114
LEU A 115
 None
 0.50A 5i1pD-3ntvA:
undetectable		 5i1pD-3ntvA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 VAL A  55
GLU A  77
GLY A  79
TYR A  84
ALA A 131
PHE A 147
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
None
 0.46A 5n5dA-3ntvA:
22.8		 5n5dA-3ntvA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 VAL A  55
GLU A  77
TYR A  84
ILE A 101
ALA A 131
PHE A 147
 SO4  A 233 (-4.2A)
SO4  A 233 (-4.0A)
SO4  A 233 (-4.9A)
None
None
None
 0.48A 5n5dB-3ntvA:
22.8		 5n5dB-3ntvA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		4 / 4 VAL A  55
LEU A  62
ASN A 176
ASP A 149
 SO4  A 233 (-4.2A)
None
None
None
 1.37A 5vcyA-3ntvA:
undetectable		 5vcyA-3ntvA:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		6 / 12 GLU A  77
GLY A  79
ASN A 104
ALA A 131
ALA A 153
PHE A 158
 SO4  A 233 (-4.0A)
None
None
None
None
None
 0.90A 5zw4A-3ntvA:
29.6		 5zw4A-3ntvA:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		8 / 12 PRO A  53
ILE A  54
GLU A  77
GLY A  79
ALA A  81
TYR A  84
ASN A 104
ALA A 131
 None
SO4  A 233 (-3.7A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-3.6A)
SO4  A 233 (-4.9A)
None
None
 0.67A 5zw4A-3ntvA:
29.6		 5zw4A-3ntvA:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3ntv MW1564 PROTEIN
(Staphylococcus
aureus) 		8 / 12 PRO A  53
ILE A  54
GLU A  77
GLY A  79
TYR A  84
ASN A 104
ALA A 131
PHE A 158
 None
SO4  A 233 (-3.7A)
SO4  A 233 (-4.0A)
None
SO4  A 233 (-4.9A)
None
None
None
 0.68A 5zw4A-3ntvA:
29.6		 5zw4A-3ntvA:
36.10