SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 11 ALA A 187
THR A 116
LEU A 257
ALA A 256
LEU A 268
 None
 0.98A 1jinA-3nu1A:
undetectable		 1jinA-3nu1A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 10 ILE A 185
GLY A 190
GLY A 189
PRO A 118
THR A 117
 None
 1.00A 1k6cA-3nu1A:
undetectable		 1k6cA-3nu1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		4 / 6 PRO A 113
LYS A 124
MET A 123
ALA A 122
 None
 1.27A 1qhyA-3nu1A:
undetectable		 1qhyA-3nu1A:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		4 / 6 LEU A  99
VAL A  98
VAL A  68
ASP A  53
 None
 1.15A 3fwgA-3nu1A:
undetectable		 3fwgA-3nu1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 12 LEU A 268
GLY A 190
GLY A 189
PRO A 156
ALA A 183
 None
 1.22A 3i5uA-3nu1A:
2.4		 3i5uA-3nu1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		3 / 3 PRO A 242
THR A 241
LEU A 216
 None
 0.79A 3ttrA-3nu1A:
undetectable		 3ttrA-3nu1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		4 / 5 GLY A  34
GLY A  33
MET A  71
GLU A  38
 None
 1.25A 4fglC-3nu1A:
undetectable		 4fglC-3nu1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 10 GLY A 259
GLY A 261
GLU A 263
GLY A  34
ILE A  39
 None
 0.81A 5aqfA-3nu1A:
undetectable		 5aqfA-3nu1A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 10 GLY A 259
GLY A 261
GLU A 263
GLY A  34
ILE A  39
 None
 0.80A 5aqfC-3nu1A:
undetectable		 5aqfC-3nu1A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		5 / 10 GLY A 259
GLY A 261
GLU A 263
GLY A  34
ILE A  39
 None
 0.81A 5aqyA-3nu1A:
2.1		 5aqyA-3nu1A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN
(Yersinia
pestis) 		4 / 8 ALA A 103
ILE A  79
ALA A  76
LEU A  80
 None
 0.81A 5te8B-3nu1A:
undetectable		 5te8B-3nu1A:
20.00