SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nu8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 286
LEU A 298
VAL A 294
LEU A 263
 None
 0.79A 1cqpA-3nu8A:
undetectable
1cqpB-3nu8A:
undetectable		 1cqpA-3nu8A:
19.83
1cqpB-3nu8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 9 CYH A 354
LEU A 357
LEU A 298
ILE A   2
ILE A 350
 None
 1.47A 1hzeA-3nu8A:
undetectable
1hzeB-3nu8A:
undetectable		 1hzeA-3nu8A:
13.48
1hzeB-3nu8A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 350
CYH A 354
LEU A 357
LEU A 298
ILE A   2
 None
 1.46A 1hzeA-3nu8A:
undetectable
1hzeB-3nu8A:
undetectable		 1hzeA-3nu8A:
13.48
1hzeB-3nu8A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 187
PHE A 161
LEU A 238
LEU A  40
ALA A 195
 None
 1.38A 2bxeA-3nu8A:
undetectable		 2bxeA-3nu8A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.31A 2eimJ-3nu8A:
undetectable		 2eimJ-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.33A 2eimW-3nu8A:
undetectable		 2eimW-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A   4
LEU A 357
VAL A 294
MET A 337
LEU A 345
 None
 1.34A 2prgB-3nu8A:
undetectable		 2prgB-3nu8A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 10 THR A  60
THR A  80
VAL A  86
VAL A 130
ILE A 128
 LLP  A 185 ( 3.7A)
None
None
None
None
 1.28A 2qboA-3nu8A:
undetectable		 2qboA-3nu8A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.47A 3ag1J-3nu8A:
undetectable		 3ag1J-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 342
ILE A   2
PRO A 304
PRO A 340
 None
 1.00A 3fxrA-3nu8A:
undetectable		 3fxrA-3nu8A:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  65
ALA A  62
ALA A  87
THR A  91
 None
None
LLP  A 185 ( 3.6A)
None
 1.07A 3mdrB-3nu8A:
undetectable		 3mdrB-3nu8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 8 ALA A  62
ILE A 196
ALA A 157
ALA A 158
 None
None
None
LLP  A 185 ( 3.3A)
 0.76A 3r9tA-3nu8A:
undetectable		 3r9tA-3nu8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  18
ILE A  22
ALA A 235
THR A 232
VAL A  25
 None
 1.02A 3rukB-3nu8A:
undetectable		 3rukB-3nu8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  18
ILE A  22
ALA A 235
THR A 232
VAL A  25
 None
 1.08A 4nkvA-3nu8A:
undetectable		 4nkvA-3nu8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 8 THR A  80
PRO A  81
LEU A  63
SER A 131
 None
 1.12A 4qknA-3nu8A:
undetectable		 4qknA-3nu8A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 202
ILE A 222
ALA A  69
 None
 0.63A 4wnwB-3nu8A:
undetectable		 4wnwB-3nu8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  87
GLN A 159
GLU A 155
ASN A 110
TYR A 309
 LLP  A 185 ( 3.6A)
LLP  A 185 ( 3.6A)
None
None
None
 1.33A 4zj8A-3nu8A:
undetectable		 4zj8A-3nu8A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 242
PHE A 245
PHE A  47
THR A 179
LEU A 173
 None
 0.90A 5iepA-3nu8A:
undetectable		 5iepA-3nu8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 156
GLU A 155
LEU A 238
LEU A 187
SER A 170
 LLP  A 185 ( 2.9A)
None
None
None
None
 1.10A 5nd7B-3nu8A:
undetectable		 5nd7B-3nu8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.41A 5wauJ-3nu8A:
undetectable		 5wauJ-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.26A 5x1fW-3nu8A:
undetectable		 5x1fW-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nu8 AMINOTRANSFERASE
WBPE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.34A 6nknW-3nu8A:
undetectable		 6nknW-3nu8A:
12.45