SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		5 / 12 ASP A 176
ILE A 175
TRP A 202
ASP A 213
ARG A 217
 AMP  A 242 (-3.4A)
None
None
None
None
 1.36A 2qmjA-3nuaA:
undetectable		 2qmjA-3nuaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		5 / 12 ASP A 176
ILE A 175
TRP A 202
ASP A 213
ARG A 217
 AMP  A 242 (-3.4A)
None
None
None
None
 1.40A 3phaC-3nuaA:
undetectable		 3phaC-3nuaA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		5 / 12 ASP A 176
ILE A 175
TRP A 202
ASP A 213
ARG A 217
 AMP  A 242 (-3.4A)
None
None
None
None
 1.39A 3phaD-3nuaA:
undetectable		 3phaD-3nuaA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		3 / 3 THR A  34
ASP A 126
GLU A  91
 CIT  A 243 (-3.9A)
None
AMP  A 242 (-4.2A)
 0.81A 3qowA-3nuaA:
undetectable		 3qowA-3nuaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 6 GLU A 187
GLY A 186
LEU A 189
TYR A 184
 None
 0.90A 3w9tB-3nuaA:
undetectable		 3w9tB-3nuaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 6 GLU A 187
GLY A 186
LEU A 189
TYR A 184
 None
 0.89A 3w9tE-3nuaA:
undetectable		 3w9tE-3nuaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 6 GLU A 187
GLY A 186
LEU A 189
TYR A 184
 None
 0.88A 3w9tF-3nuaA:
undetectable		 3w9tF-3nuaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 8 TYR A 226
VAL A 229
ILE A 172
GLU A 193
 None
 1.09A 4a97G-3nuaA:
undetectable		 4a97G-3nuaA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 7 TYR A 226
VAL A 229
ILE A 172
GLU A 193
 None
 1.14A 4a97H-3nuaA:
undetectable		 4a97H-3nuaA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 6 GLY A 207
ARG A 214
GLU A 228
ARG A 232
 None
 1.24A 4bqfA-3nuaA:
undetectable		 4bqfA-3nuaA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 7 ASP A 176
ILE A 175
GLY A 111
TRP A 202
 AMP  A 242 (-3.4A)
None
None
None
 0.87A 4zxiA-3nuaA:
undetectable		 4zxiA-3nuaA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 5 GLU A 193
LYS A  14
ASP A 192
GLU A 180
 None
ADP  A 241 (-2.7A)
ADP  A 241 (-4.1A)
ADP  A 241 (-3.3A)
 1.25A 5a06A-3nuaA:
undetectable		 5a06A-3nuaA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 7 ARG A 217
ARG A  95
ASP A 176
ILE A 175
 None
AMP  A 242 (-3.1A)
AMP  A 242 (-3.4A)
None
 1.06A 5a06B-3nuaA:
undetectable		 5a06B-3nuaA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		3 / 3 THR A  34
ASP A 126
GLU A  91
 CIT  A 243 (-3.9A)
None
AMP  A 242 (-4.2A)
 0.84A 5fa8A-3nuaA:
undetectable		 5fa8A-3nuaA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		3 / 3 TRP A 202
GLU A 110
ASP A 176
 None
None
AMP  A 242 (-3.4A)
 1.06A 5gqbA-3nuaA:
undetectable		 5gqbA-3nuaA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))		 3nua PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Clostridium
perfringens) 		4 / 5 ASP A 213
ARG A 217
ARG A 216
LEU A 114
 None
None
AMP  A 242 ( 3.3A)
None
 0.98A 5tuiB-3nuaA:
undetectable		 5tuiB-3nuaA:
21.90